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TRIM25 activates AKT/mTOR by inhibiting PTEN via K63-linked polyubiquitination in non-small cell lung cancer.
He, Yuan-Ming; Zhou, Xiu-Min; Jiang, Shuo-Yi; Zhang, Zu-Bin; Cao, Bi-Yin; Liu, Jin-Bao; Zeng, Yuan-Ying; Zhao, Jun; Mao, Xin-Liang.
Afiliação
  • He YM; Guangdong Key Laboratory of Protein Modification and Degradation, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, 511436, China.
  • Zhou XM; Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, 215123, China.
  • Jiang SY; Department of Oncology, The First Affiliated Hospital of Soochow University, Suzhou, 215106, China.
  • Zhang ZB; Guangdong Key Laboratory of Protein Modification and Degradation, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, 511436, China.
  • Cao BY; Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, 215123, China.
  • Liu JB; Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, 215123, China.
  • Zeng YY; Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, 215123, China.
  • Zhao J; Guangdong Key Laboratory of Protein Modification and Degradation, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, 511436, China.
  • Mao XL; Department of Oncology, Suzhou Municipal Hospital, Suzhou, 215100, China. zengyuanying@163.com.
Acta Pharmacol Sin ; 43(3): 681-691, 2022 Mar.
Article em En | MEDLINE | ID: mdl-33931764
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Proteínas de Ligação a DNA / PTEN Fosfo-Hidrolase / Proteínas Proto-Oncogênicas c-akt / Serina-Treonina Quinases TOR / Neoplasias Pulmonares Limite: Humans Idioma: En Revista: Acta Pharmacol Sin Assunto da revista: FARMACOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Proteínas de Ligação a DNA / PTEN Fosfo-Hidrolase / Proteínas Proto-Oncogênicas c-akt / Serina-Treonina Quinases TOR / Neoplasias Pulmonares Limite: Humans Idioma: En Revista: Acta Pharmacol Sin Assunto da revista: FARMACOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China