Shining light on the neuro-immune axis in the gut.

Stakenborg, Nathalie; Boeckxstaens, Guy E

Stakenborg, Nathalie; Boeckxstaens, Guy E.

Afiliação

Stakenborg N; Center of Intestinal Neuro-immune Interaction, Translational Research Center for GI Disorders (TARGID), Department of Chronic Diseases, Metabolism and Ageing, KU Leuven - University of Leuven, Leuven, Belgium.
Boeckxstaens GE; Center of Intestinal Neuro-immune Interaction, Translational Research Center for GI Disorders (TARGID), Department of Chronic Diseases, Metabolism and Ageing, KU Leuven - University of Leuven, Leuven, Belgium. Electronic address: guy.boeckxstaens@kuleuven.be.

Immunity ; 54(5): 850-852, 2021 05 11.

Article em En | MEDLINE | ID: mdl-33979582

ABSTRACT

ABSTRACT

In this issue of Immunity, Schiller et al. report that local sympathetic nerve activation decreases endothelial expression of the adhesion molecule MAdCAM-1, reducing immune cell infiltration and colitis-induced inflammation. These findings suggest that local sympathetic stimulation provides a key gateway for regulating organ homeostasis.

Assuntos

Colite; Mucoproteínas; Moléculas de Adesão Celular; Endotélio; Humanos; Neuroimunomodulação

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Colite / Mucoproteínas Limite: Humans Idioma: En Revista: Immunity Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Bélgica

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