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Cytoplasmic FUS triggers early behavioral alterations linked to cortical neuronal hyperactivity and inhibitory synaptic defects.
Scekic-Zahirovic, Jelena; Sanjuan-Ruiz, Inmaculada; Kan, Vanessa; Megat, Salim; De Rossi, Pierre; Dieterlé, Stéphane; Cassel, Raphaelle; Jamet, Marguerite; Kessler, Pascal; Wiesner, Diana; Tzeplaeff, Laura; Demais, Valérie; Sahadevan, Sonu; Hembach, Katharina M; Muller, Hans-Peter; Picchiarelli, Gina; Mishra, Nibha; Antonucci, Stefano; Dirrig-Grosch, Sylvie; Kassubek, Jan; Rasche, Volker; Ludolph, Albert; Boutillier, Anne-Laurence; Roselli, Francesco; Polymenidou, Magdalini; Lagier-Tourenne, Clotilde; Liebscher, Sabine; Dupuis, Luc.
Afiliação
  • Scekic-Zahirovic J; Université de Strasbourg, Inserm, Mécanismes centraux et périphériques de la neurodégénérescence, Strasbourg, France.
  • Sanjuan-Ruiz I; Université de Strasbourg, Inserm, Mécanismes centraux et périphériques de la neurodégénérescence, Strasbourg, France.
  • Kan V; Institute of Clinical Neuroimmunology, Klinikum der Universität München, Ludwig-Maximilians-University Munich, Munich, Germany.
  • Megat S; BioMedical Center, Medical Faculty, Ludwig-Maximilians-University Munich, Munich, Germany.
  • De Rossi P; Université de Strasbourg, Inserm, Mécanismes centraux et périphériques de la neurodégénérescence, Strasbourg, France.
  • Dieterlé S; Department of Quantitative Biomedicine, University of Zurich, Zürich, Switzerland.
  • Cassel R; Université de Strasbourg, Inserm, Mécanismes centraux et périphériques de la neurodégénérescence, Strasbourg, France.
  • Jamet M; Université de Strasbourg, Inserm, Mécanismes centraux et périphériques de la neurodégénérescence, Strasbourg, France.
  • Kessler P; Université de Strasbourg, UMR 7364 CNRS, Laboratoire de Neurosciences Cognitives et Adaptatives (LNCA), Strasbourg, France.
  • Wiesner D; Université de Strasbourg, Inserm, Mécanismes centraux et périphériques de la neurodégénérescence, Strasbourg, France.
  • Tzeplaeff L; Université de Strasbourg, Inserm, Unité mixte de service du CRBS, UMS 038, Strasbourg, France.
  • Demais V; Department of Neurology, Ulm University, Ulm, Germany.
  • Sahadevan S; Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Ulm, Germany.
  • Hembach KM; Université de Strasbourg, UMR 7364 CNRS, Laboratoire de Neurosciences Cognitives et Adaptatives (LNCA), Strasbourg, France.
  • Muller HP; Plateforme Imagerie In Vitro, CNRS UPS-3156, NeuroPôle, Strasbourg, France.
  • Picchiarelli G; Department of Quantitative Biomedicine, University of Zurich, Zürich, Switzerland.
  • Mishra N; Department of Quantitative Biomedicine, University of Zurich, Zürich, Switzerland.
  • Antonucci S; Department of Neurology, Ulm University, Ulm, Germany.
  • Dirrig-Grosch S; Université de Strasbourg, Inserm, Mécanismes centraux et périphériques de la neurodégénérescence, Strasbourg, France.
  • Kassubek J; Department of Neurology, The Sean M. Healey and AMG Center for ALS at Mass General, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • Rasche V; Broad Institute of Harvard University and MIT, Cambridge, MA, USA.
  • Ludolph A; Department of Neurology, Ulm University, Ulm, Germany.
  • Boutillier AL; Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Ulm, Germany.
  • Roselli F; Université de Strasbourg, Inserm, Mécanismes centraux et périphériques de la neurodégénérescence, Strasbourg, France.
  • Polymenidou M; Department of Neurology, Ulm University, Ulm, Germany.
  • Lagier-Tourenne C; Ulm University Medical Center, Department of Internal Medicine II, Ulm, Germany.
  • Liebscher S; Department of Neurology, Ulm University, Ulm, Germany.
  • Dupuis L; Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Ulm, Germany.
Nat Commun ; 12(1): 3028, 2021 05 21.
Article em En | MEDLINE | ID: mdl-34021132
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sinapses / Citoplasma / Proteína FUS de Ligação a RNA / Esclerose Lateral Amiotrófica Limite: Animals Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: França
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sinapses / Citoplasma / Proteína FUS de Ligação a RNA / Esclerose Lateral Amiotrófica Limite: Animals Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: França