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Chromosomal copy number heterogeneity predicts survival rates across cancers.
van Dijk, Erik; van den Bosch, Tom; Lenos, Kristiaan J; El Makrini, Khalid; Nijman, Lisanne E; van Essen, Hendrik F B; Lansu, Nico; Boekhout, Michiel; Hageman, Joris H; Fitzgerald, Rebecca C; Punt, Cornelis J A; Tuynman, Jurriaan B; Snippert, Hugo J G; Kops, Geert J P L; Medema, Jan Paul; Ylstra, Bauke; Vermeulen, Louis; Miedema, Daniël M.
Afiliação
  • van Dijk E; Department of Pathology, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
  • van den Bosch T; LEXOR, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam and Amsterdam Gastroenterology & Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
  • Lenos KJ; Oncode Institute, Amsterdam, The Netherlands.
  • El Makrini K; LEXOR, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam and Amsterdam Gastroenterology & Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
  • Nijman LE; Oncode Institute, Amsterdam, The Netherlands.
  • van Essen HFB; LEXOR, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam and Amsterdam Gastroenterology & Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
  • Lansu N; Oncode Institute, Amsterdam, The Netherlands.
  • Boekhout M; LEXOR, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam and Amsterdam Gastroenterology & Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
  • Hageman JH; Oncode Institute, Amsterdam, The Netherlands.
  • Fitzgerald RC; Department of Pathology, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
  • Punt CJA; Oncode Institute, Amsterdam, The Netherlands.
  • Tuynman JB; Hubrecht institute-KNAW and University Medical Center Utrecht, Utrecht, The Netherlands.
  • Snippert HJG; Oncode Institute, Amsterdam, The Netherlands.
  • Kops GJPL; Center for Molecular Medicine, University Medical Centre Utrecht, Utrecht, The Netherlands.
  • Medema JP; Oncode Institute, Amsterdam, The Netherlands.
  • Ylstra B; Center for Molecular Medicine, University Medical Centre Utrecht, Utrecht, The Netherlands.
  • Vermeulen L; MRC Cancer Unit, University of Cambridge, Cambridge, UK.
  • Miedema DM; Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.
Nat Commun ; 12(1): 3188, 2021 05 27.
Article em En | MEDLINE | ID: mdl-34045449
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Heterogeneidade Genética / Variações do Número de Cópias de DNA / Microambiente Tumoral / Modelos Genéticos / Neoplasias Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Aged80 / Child / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Holanda
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Heterogeneidade Genética / Variações do Número de Cópias de DNA / Microambiente Tumoral / Modelos Genéticos / Neoplasias Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Aged80 / Child / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Holanda