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The EP300/TP53 pathway, a suppressor of the Hippo and canonical WNT pathways, is activated in human hearts with arrhythmogenic cardiomyopathy in the absence of overt heart failure.
Rouhi, Leila; Fan, Siyang; Cheedipudi, Sirisha M; Braza-Boïls, Aitana; Molina, Maria Sabater; Yao, Yan; Robertson, Matthew J; Coarfa, Cristian; Gimeno, Juan R; Molina, Pilar; Gurha, Priyatansh; Zorio, Esther; Marian, Ali J.
Afiliação
  • Rouhi L; Department of Medicine, Center for Cardiovascular Genetics, Institute of Molecular Medicine, University of Texas Health Sciences Center at Houston, 6770 Bertner Ave, Suite C900A, Houston, TX 77030, USA.
  • Fan S; Department of Medicine, Center for Cardiovascular Genetics, Institute of Molecular Medicine, University of Texas Health Sciences Center at Houston, 6770 Bertner Ave, Suite C900A, Houston, TX 77030, USA.
  • Cheedipudi SM; Department of Medicine, Center for Cardiovascular Genetics, Institute of Molecular Medicine, University of Texas Health Sciences Center at Houston, 6770 Bertner Ave, Suite C900A, Houston, TX 77030, USA.
  • Braza-Boïls A; Unidad de Cardiopatías Familiares, Muerte Súbita y Mecanismos de Enfermedad (CaFaMuSMe), Instituto de Investigación Sanitaria La Fe, Valencia, Spain.
  • Molina MS; Center for Biomedical Network Research on Cardiovascular Diseases (CIBERCV), Madrid, Spain.
  • Yao Y; Department of Genetics and Microbiology, Cardiogenetic Laboratory, Instituto Murciano de Investigación Biosanitaria, Murcia, Spain.
  • Robertson MJ; Department of Cardiology, Fuwai Hospital, Peking Union Medical College, Beijing, China.
  • Coarfa C; Department of Cell Biology, Baylor College of Medicine, Houston, TX 77030, USA.
  • Gimeno JR; Department of Cell Biology, Baylor College of Medicine, Houston, TX 77030, USA.
  • Molina P; Center for Biomedical Network Research on Cardiovascular Diseases (CIBERCV), Madrid, Spain.
  • Gurha P; Department of Cardiology, Unidad CSUR Cardiopatias Familiares, Hospital Universitario Virgen de la Arrixaca, Murcia, Spain.
  • Zorio E; Unidad de Cardiopatías Familiares, Muerte Súbita y Mecanismos de Enfermedad (CaFaMuSMe), Instituto de Investigación Sanitaria La Fe, Valencia, Spain.
  • Marian AJ; Servicio de Patologia, Instituto de Medicina Legal y Ciencias Forenses de Valencia, Histology Unit at the Universitat de València, Valencian, Spain.
Cardiovasc Res ; 118(6): 1466-1478, 2022 05 06.
Article em En | MEDLINE | ID: mdl-34132777
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Displasia Arritmogênica Ventricular Direita / Insuficiência Cardíaca / Cardiomiopatias Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Humans Idioma: En Revista: Cardiovasc Res Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Displasia Arritmogênica Ventricular Direita / Insuficiência Cardíaca / Cardiomiopatias Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Humans Idioma: En Revista: Cardiovasc Res Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos