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Chemical Modulation of the 1-(Piperidin-4-yl)-1,3-dihydro-2H-benzo[d]imidazole-2-one Scaffold as a Novel NLRP3 Inhibitor.
Gastaldi, Simone; Boscaro, Valentina; Gianquinto, Eleonora; Sandall, Christina F; Giorgis, Marta; Marini, Elisabetta; Blua, Federica; Gallicchio, Margherita; Spyrakis, Francesca; MacDonald, Justin A; Bertinaria, Massimo.
Afiliação
  • Gastaldi S; Department of Drug Science and Technology, University of Turin, Via Giuria 9, 10125 Torino, Italy.
  • Boscaro V; Department of Drug Science and Technology, University of Turin, Via Giuria 9, 10125 Torino, Italy.
  • Gianquinto E; Department of Drug Science and Technology, University of Turin, Via Giuria 9, 10125 Torino, Italy.
  • Sandall CF; Department of Biochemistry & Molecular Biology, Cumming School of Medicine, University of Calgary, 3280 Hospital Drive NW, Calgary, AB T2N 4Z6, Canada.
  • Giorgis M; Department of Drug Science and Technology, University of Turin, Via Giuria 9, 10125 Torino, Italy.
  • Marini E; Department of Drug Science and Technology, University of Turin, Via Giuria 9, 10125 Torino, Italy.
  • Blua F; Department of Drug Science and Technology, University of Turin, Via Giuria 9, 10125 Torino, Italy.
  • Gallicchio M; Department of Drug Science and Technology, University of Turin, Via Giuria 9, 10125 Torino, Italy.
  • Spyrakis F; Department of Drug Science and Technology, University of Turin, Via Giuria 9, 10125 Torino, Italy.
  • MacDonald JA; Department of Biochemistry & Molecular Biology, Cumming School of Medicine, University of Calgary, 3280 Hospital Drive NW, Calgary, AB T2N 4Z6, Canada.
  • Bertinaria M; Department of Drug Science and Technology, University of Turin, Via Giuria 9, 10125 Torino, Italy.
Molecules ; 26(13)2021 Jun 29.
Article em En | MEDLINE | ID: mdl-34209843
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Interleucina-1beta / Piroptose / Proteína 3 que Contém Domínio de Pirina da Família NLR / Imidazóis / Macrófagos Limite: Humans Idioma: En Revista: Molecules Assunto da revista: BIOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Itália
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Interleucina-1beta / Piroptose / Proteína 3 que Contém Domínio de Pirina da Família NLR / Imidazóis / Macrófagos Limite: Humans Idioma: En Revista: Molecules Assunto da revista: BIOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Itália