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Discovery and Characterisation of Highly Cooperative FAK-Degrading PROTACs.
Law, Robert P; Nunes, Joao; Chung, Chun-Wa; Bantscheff, Marcus; Buda, Karol; Dai, Han; Evans, John P; Flinders, Adam; Klimaszewska, Diana; Lewis, Antonia J; Muelbaier, Marcel; Scott-Stevens, Paul; Stacey, Peter; Tame, Christopher J; Watt, Gillian F; Zinn, Nico; Queisser, Markus A; Harling, John D; Benowitz, Andrew B.
Afiliação
  • Law RP; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK.
  • Nunes J; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK.
  • Chung CW; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK.
  • Bantscheff M; Cellzome GmbH, a GSK company, Meyerhofstraße 1, 69117, Heidelberg, Germany.
  • Buda K; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK.
  • Dai H; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK.
  • Evans JP; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK.
  • Flinders A; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK.
  • Klimaszewska D; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK.
  • Lewis AJ; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK.
  • Muelbaier M; Cellzome GmbH, a GSK company, Meyerhofstraße 1, 69117, Heidelberg, Germany.
  • Scott-Stevens P; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK.
  • Stacey P; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK.
  • Tame CJ; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK.
  • Watt GF; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK.
  • Zinn N; Cellzome GmbH, a GSK company, Meyerhofstraße 1, 69117, Heidelberg, Germany.
  • Queisser MA; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK.
  • Harling JD; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK.
  • Benowitz AB; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK.
Angew Chem Int Ed Engl ; 60(43): 23327-23334, 2021 10 18.
Article em En | MEDLINE | ID: mdl-34416073

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinase 1 de Adesão Focal / Proteólise / Antineoplásicos Limite: Animals / Humans Idioma: En Revista: Angew Chem Int Ed Engl Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinase 1 de Adesão Focal / Proteólise / Antineoplásicos Limite: Animals / Humans Idioma: En Revista: Angew Chem Int Ed Engl Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido