Different Aspects of Classical Pathway Overactivation in Patients With C3 Glomerulopathy and Immune Complex-Mediated Membranoproliferative Glomerulonephritis.

Michels, Marloes A H M; van de Kar, Nicole C A J; van Kraaij, Sanne A W; Sarlea, Sebastian A; Gracchi, Valentina; Engels, Flore A P T; Dorresteijn, Eiske M; van der Deure, Johannes; Duineveld, Caroline; Wetzels, Jack F M; van den Heuvel, Lambertus P W J; Volokhina, Elena B

Michels, Marloes A H M; van de Kar, Nicole C A J; van Kraaij, Sanne A W; Sarlea, Sebastian A; Gracchi, Valentina; Engels, Flore A P T; Dorresteijn, Eiske M; van der Deure, Johannes; Duineveld, Caroline; Wetzels, Jack F M; van den Heuvel, Lambertus P W J; Volokhina, Elena B.

Afiliação

Michels MAHM; Department of Pediatric Nephrology, Radboud Institute for Molecular Life Sciences, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, Netherlands.
van de Kar NCAJ; Department of Pediatric Nephrology, Radboud Institute for Molecular Life Sciences, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, Netherlands.
van Kraaij SAW; Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, Netherlands.
Sarlea SA; Department of Pediatric Nephrology, Radboud Institute for Molecular Life Sciences, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, Netherlands.
Gracchi V; Department of Pediatric Nephrology, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
Engels FAPT; Department of Pediatric Nephrology, Maastricht University Medical Center+, Maastricht, Netherlands.
Dorresteijn EM; Department of Pediatric Nephrology, Sophia Children's Hospital, Erasmus Medical Center, Rotterdam, Netherlands.
van der Deure J; Department of Pediatrics, Deventer Hospital, Deventer, Netherlands.
Duineveld C; Department of Nephrology, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, Netherlands.
Wetzels JFM; Department of Nephrology, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, Netherlands.
van den Heuvel LPWJ; Department of Pediatric Nephrology, Radboud Institute for Molecular Life Sciences, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, Netherlands.
Volokhina EB; Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, Netherlands.

Front Immunol ; 12: 715704, 2021.

Article em En | MEDLINE | ID: mdl-34456924

Assuntos

Complexo Antígeno-Anticorpo/imunologia; Complemento C3/imunologia; Via Clássica do Complemento/imunologia; Glomerulonefrite Membranoproliferativa/etiologia; Glomerulonefrite Membranoproliferativa/metabolismo; Adolescente; Animais; Autoanticorpos/imunologia; Biomarcadores; Criança; Ativação do Complemento; Complemento C3/metabolismo; C3 Convertase da Via Alternativa do Complemento/imunologia; Fator Nefrítico do Complemento 3/imunologia; Proteínas do Sistema Complemento/imunologia; Suscetibilidade a Doenças; Ativação Enzimática; Feminino; Seguimentos; Predisposição Genética para Doença; Glomerulonefrite Membranoproliferativa/diagnóstico; Humanos; Masculino

Palavras-chave

C3 convertase; C3 glomerulopathy; C3 nephritic factors (C3NeFs); C4 nephritic factors (C4NeFs); autoantibody; classical complement pathway

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Complemento C3 / Glomerulonefrite Membranoproliferativa / Via Clássica do Complemento / Complexo Antígeno-Anticorpo Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Animals / Child / Female / Humans / Male Idioma: En Revista: Front Immunol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Holanda

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google