[Multiple skull base defects: features of pathogenesis, diagnosis and treatment]. / Mnozhestvennye defekty osnovaniya cherepa: osobennosti patogeneza, diagnostiki i lecheniya.
Zh Vopr Neirokhir Im N N Burdenko
; 85(4): 58-63, 2021.
Article
em Ru
| MEDLINE
| ID: mdl-34463451
ABSTRACT
OBJECTIVE:
To determine the risk factors of multiple skull base defects, as well as features of diagnosis and treatment of this pathology. MATERIAL ANDMETHODS:
A retrospective analysis included 39 patients who underwent surgery for nasal CSF leakage at the Burdenko Neurosurgical Center in 2000-2019. The study recruited patients with multiple simultant skull base defects.RESULTS:
Traumatic defects were observed in 23 (59%) patients, spontaneous defects - in 16 (41%) cases. All patients underwent endoscopic endonasal closure of skull base defects with autografts.CONCLUSION:
Multiple defects are more common in severe traumatic brain injury. The main risk factors of multiple spontaneous defects are female sex and overweight. Adequate diagnosis implies high-resolution CT (slice width 0.5-1 mm), as well as intraoperative control of all suspicious and «weak¼ areas. Endoscopic endonasal technique is effective and safe for multiple skull base defects (efficiency 97%).Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Base do Crânio
/
Procedimentos de Cirurgia Plástica
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
Idioma:
Ru
Revista:
Zh Vopr Neirokhir Im N N Burdenko
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Federação Russa