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Interprotomer disulfide-stabilized variants of the human metapneumovirus fusion glycoprotein induce high titer-neutralizing responses.
Stewart-Jones, Guillaume B E; Gorman, Jason; Ou, Li; Zhang, Baoshan; Joyce, M Gordon; Yang, Lijuan; Cheng, Cheng; Chuang, Gwo-Yu; Foulds, Kathryn E; Kong, Wing-Pui; Olia, Adam S; Sastry, Mallika; Shen, Chen-Hsiang; Todd, John-Paul; Tsybovsky, Yaroslav; Verardi, Raffaello; Yang, Yongping; Collins, Peter L; Corti, Davide; Lanzavecchia, Antonio; Scorpio, Diana G; Mascola, John R; Buchholz, Ursula J; Kwong, Peter D.
Afiliação
  • Stewart-Jones GBE; Vaccine Research Center, NIH, Bethesda, MD 20892.
  • Gorman J; Vaccine Research Center, NIH, Bethesda, MD 20892.
  • Ou L; National Resource for Automated Molecular Microscopy, Simons Electron Microscopy Center, New York Structural Biology Center, New York, NY 10027.
  • Zhang B; Vaccine Research Center, NIH, Bethesda, MD 20892.
  • Joyce MG; Vaccine Research Center, NIH, Bethesda, MD 20892.
  • Yang L; Vaccine Research Center, NIH, Bethesda, MD 20892.
  • Cheng C; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Silver Spring, MD 20910.
  • Chuang GY; Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892.
  • Foulds KE; Vaccine Research Center, NIH, Bethesda, MD 20892.
  • Kong WP; Vaccine Research Center, NIH, Bethesda, MD 20892.
  • Olia AS; Vaccine Research Center, NIH, Bethesda, MD 20892.
  • Sastry M; Vaccine Research Center, NIH, Bethesda, MD 20892.
  • Shen CH; Vaccine Research Center, NIH, Bethesda, MD 20892.
  • Todd JP; Vaccine Research Center, NIH, Bethesda, MD 20892.
  • Tsybovsky Y; Vaccine Research Center, NIH, Bethesda, MD 20892.
  • Verardi R; Vaccine Research Center, NIH, Bethesda, MD 20892.
  • Yang Y; Electron Microscopy Laboratory, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD 21701.
  • Collins PL; Vaccine Research Center, NIH, Bethesda, MD 20892.
  • Corti D; Vaccine Research Center, NIH, Bethesda, MD 20892.
  • Lanzavecchia A; Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892.
  • Scorpio DG; Institute for Research in Biomedicine, Università della Svizzera italiana, 6500 Bellinzona, Switzerland.
  • Mascola JR; Humabs BioMed SA, 6500 Bellinzona, Switzerland.
  • Buchholz UJ; Institute for Research in Biomedicine, Università della Svizzera italiana, 6500 Bellinzona, Switzerland.
  • Kwong PD; Vaccine Research Center, NIH, Bethesda, MD 20892.
Proc Natl Acad Sci U S A ; 118(39)2021 09 28.
Article em En | MEDLINE | ID: mdl-34551978
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glicoproteínas / Metapneumovirus / Dissulfetos / Anticorpos Neutralizantes / Anticorpos Antivirais / Mutação / Epitopos Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glicoproteínas / Metapneumovirus / Dissulfetos / Anticorpos Neutralizantes / Anticorpos Antivirais / Mutação / Epitopos Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2021 Tipo de documento: Article