Your browser doesn't support javascript.
loading
Thioridazine reverts the phenotype in cellular and Drosophila models of amyotrophic lateral sclerosis by enhancing TDP-43 aggregate clearance.
Cragnaz, Lucia; Spinelli, Greta; De Conti, Laura; Bureau, Emilie A; Brownlees, Janet; Feiguin, Fabian; Romano, Valentina; Skoko, Natasa; Klima, Raffaella; Kettleborough, Catherine A; Baralle, Francisco E; Baralle, Marco.
Afiliação
  • Cragnaz L; International Centre for Genetic Engineering and Biotechnology (ICGEB), Padriciano 99, 34149 Trieste, Italy.
  • Spinelli G; International Centre for Genetic Engineering and Biotechnology (ICGEB), Padriciano 99, 34149 Trieste, Italy.
  • De Conti L; International Centre for Genetic Engineering and Biotechnology (ICGEB), Padriciano 99, 34149 Trieste, Italy.
  • Bureau EA; LifeArc, Accelerator Building, Open Innovation Campus, Stevenage SG1 2FX, United Kingdom.
  • Brownlees J; LifeArc, Accelerator Building, Open Innovation Campus, Stevenage SG1 2FX, United Kingdom.
  • Feiguin F; International Centre for Genetic Engineering and Biotechnology (ICGEB), Padriciano 99, 34149 Trieste, Italy; Department of Life and Environmental Sciences, University of Cagliari, 09042 Monserrato, Cagliari, Italy.
  • Romano V; International Centre for Genetic Engineering and Biotechnology (ICGEB), Padriciano 99, 34149 Trieste, Italy.
  • Skoko N; International Centre for Genetic Engineering and Biotechnology (ICGEB), Padriciano 99, 34149 Trieste, Italy.
  • Klima R; International Centre for Genetic Engineering and Biotechnology (ICGEB), Padriciano 99, 34149 Trieste, Italy.
  • Kettleborough CA; LifeArc, Accelerator Building, Open Innovation Campus, Stevenage SG1 2FX, United Kingdom.
  • Baralle FE; Fondazione Italiana Fegato-Onlus, Bldg. Q, AREA Science Park, ss14, Km 163.5, Basovizza, 34149 Trieste, Italy.
  • Baralle M; International Centre for Genetic Engineering and Biotechnology (ICGEB), Padriciano 99, 34149 Trieste, Italy. Electronic address: barallem@icgeb.org.
Neurobiol Dis ; 160: 105515, 2021 12.
Article em En | MEDLINE | ID: mdl-34571136
Assuntos
Palavras-chave
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tioridazina / Antagonistas de Dopamina / Proteínas de Drosophila / Proteínas de Ligação a DNA / Agregação Patológica de Proteínas / Esclerose Lateral Amiotrófica Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Neurobiol Dis Assunto da revista: NEUROLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Itália
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tioridazina / Antagonistas de Dopamina / Proteínas de Drosophila / Proteínas de Ligação a DNA / Agregação Patológica de Proteínas / Esclerose Lateral Amiotrófica Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Neurobiol Dis Assunto da revista: NEUROLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Itália