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The leukemic oncogene EVI1 hijacks a MYC super-enhancer by CTCF-facilitated loops.
Ottema, Sophie; Mulet-Lazaro, Roger; Erpelinck-Verschueren, Claudia; van Herk, Stanley; Havermans, Marije; Arricibita Varea, Andrea; Vermeulen, Michael; Beverloo, H Berna; Gröschel, Stefan; Haferlach, Torsten; Haferlach, Claudia; J Wouters, Bas; Bindels, Eric; Smeenk, Leonie; Delwel, Ruud.
Afiliação
  • Ottema S; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
  • Mulet-Lazaro R; Oncode Institute, Utrecht, The Netherlands.
  • Erpelinck-Verschueren C; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
  • van Herk S; Oncode Institute, Utrecht, The Netherlands.
  • Havermans M; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
  • Arricibita Varea A; Oncode Institute, Utrecht, The Netherlands.
  • Vermeulen M; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
  • Beverloo HB; Oncode Institute, Utrecht, The Netherlands.
  • Gröschel S; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
  • Haferlach T; Oncode Institute, Utrecht, The Netherlands.
  • Haferlach C; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
  • J Wouters B; Oncode Institute, Utrecht, The Netherlands.
  • Bindels E; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
  • Smeenk L; Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Delwel R; A380, German Cancer Research Center, Heidelberg, Germany.
Nat Commun ; 12(1): 5679, 2021 09 28.
Article em En | MEDLINE | ID: mdl-34584081
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proto-Oncogenes / Leucemia Mieloide / Proteínas Proto-Oncogênicas c-myc / Elementos Facilitadores Genéticos / Fator de Ligação a CCCTC / Proteína do Locus do Complexo MDS1 e EVI1 Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Holanda
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proto-Oncogenes / Leucemia Mieloide / Proteínas Proto-Oncogênicas c-myc / Elementos Facilitadores Genéticos / Fator de Ligação a CCCTC / Proteína do Locus do Complexo MDS1 e EVI1 Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Holanda