Convergent HIV-1 Evolution upon Targeted Destabilization of the gp120-gp41 Interface.

Torrents de la Peña, Alba; Del Moral Sánchez, Iván; Burger, Judith A; Bontjer, Ilja; Isik, Gözde; Eggink, Dirk; van Gils, Marit J; Sanders, Rogier W

Torrents de la Peña, Alba; Del Moral Sánchez, Iván; Burger, Judith A; Bontjer, Ilja; Isik, Gözde; Eggink, Dirk; van Gils, Marit J; Sanders, Rogier W.

Afiliação

Torrents de la Peña A; Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Del Moral Sánchez I; Department of Integrative Structure and Computational Biology, The Scripps Research Institute, La Jolla, California, USA.
Burger JA; Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Bontjer I; Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Isik G; Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Eggink D; Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
van Gils MJ; Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Sanders RW; Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

J Virol ; 95(24): e0053221, 2021 11 23.

Article em En | MEDLINE | ID: mdl-34586861

Assuntos

Evolução Molecular; Proteína gp120 do Envelope de HIV/metabolismo; Proteína gp41 do Envelope de HIV/metabolismo; HIV-1/genética; Anticorpos Neutralizantes; Células HEK293; Proteína gp120 do Envelope de HIV/genética; Proteína gp41 do Envelope de HIV/genética; Humanos; Mutagênese; Mutação; Conformação Proteica; Multimerização Proteica

Palavras-chave

HIV; HIV vaccine; envelope glycoprotein; evolution

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína gp41 do Envelope de HIV / Proteína gp120 do Envelope de HIV / HIV-1 / Evolução Molecular Limite: Humans Idioma: En Revista: J Virol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Holanda

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google