Hyperendemicity of cysticercosis in Madagascar: Novel insights from school children population-based antigen prevalence study.
PLoS One
; 16(10): e0258035, 2021.
Article
em En
| MEDLINE
| ID: mdl-34597322
ABSTRACT
OBJECTIVE:
Taenia solium (Ts) cysticercosis is a neglected zoonotic disease particularly prevalent in Madagascar. Few data are available for children, current data mainly rely on antibody prevalence. We sought to determine the Ts-antigen seroprevalence-determining active cysticercosis-amongst school children from various cities in Madagascar (excluding the capital) and evaluated associated risk factors.METHODS:
In seven cities in Madagascar, the presence of cysticercosis in school children (n = 1751) was investigated in 2007 using the B158/B60 antigen (Ag)-ELISA.RESULTS:
The overall prevalence based on Ag detection was 27.7% [95%CI 10-37%]. Risk factors associated with Ag positivity were age, biotope, altitude and annual average rainfall.CONCLUSION:
These results highlight the high prevalence of active cysticercosis in Madagascar among school children in an urban setting. This high prevalence as well as the risk factors unraveled point to the emergency to implement appropriate Public Health measure son a national scale.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cisticercose
/
Anticorpos Anti-Helmínticos
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Animals
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
País/Região como assunto:
Africa
Idioma:
En
Revista:
PLoS One
Assunto da revista:
CIENCIA
/
MEDICINA
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Madagascar