Remodelin, a N-acetyltransferase 10 (NAT10) inhibitor, alters mitochondrial lipid metabolism in cancer cells.

Dalhat, Mahmood Hassan; Mohammed, Mohammed Razeeth Shait; Ahmad, Abrar; Khan, Mohammad Imran; Choudhry, Hani

Dalhat, Mahmood Hassan; Mohammed, Mohammed Razeeth Shait; Ahmad, Abrar; Khan, Mohammad Imran; Choudhry, Hani.

Afiliação

Dalhat MH; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia.
Mohammed MRS; Centre for Artificial Intelligence in Precision Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
Ahmad A; Cancer and Mutagenesis Research Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia.
Khan MI; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia.
Choudhry H; Centre for Artificial Intelligence in Precision Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.

J Cell Biochem ; 122(12): 1936-1945, 2021 12.

Article em En | MEDLINE | ID: mdl-34605570

Assuntos

Hidrazonas/farmacologia; Metabolismo dos Lipídeos/efeitos dos fármacos; Mitocôndrias/metabolismo; Acetiltransferases N-Terminal/antagonistas & inibidores; Proteínas de Neoplasias/antagonistas & inibidores; Neoplasias/metabolismo; Tiazóis/farmacologia; Células HCT116; Humanos; Células MCF-7; Acetiltransferases N-Terminal/metabolismo; Proteínas de Neoplasias/metabolismo; Neoplasias/tratamento farmacológico

Palavras-chave

NAT10; cancer; metabolomics; remodelin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tiazóis / Metabolismo dos Lipídeos / Acetiltransferases N-Terminal / Hidrazonas / Mitocôndrias / Proteínas de Neoplasias / Neoplasias Limite: Humans Idioma: En Revista: J Cell Biochem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Arábia Saudita

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