Pharmacological Inhibition of Mammalian Target of Rapamycin Attenuates Deoxycorticosterone Acetate Salt-Induced Hypertension and Related Pathophysiology: Regulation of Oxidative Stress, Inflammation, and Cardiovascular Hypertrophy in Male Rats.

Temiz-Resitoglu, Meryem; Guden, Demet S; Senol, Sefika P; Vezir, Ozden; Sucu, Nehir; Kibar, Deniz; Yilmaz, Sakir N; Tunctan, Bahar; Malik, Kafait U; Sahan-Firat, Seyhan

Temiz-Resitoglu, Meryem; Guden, Demet S; Senol, Sefika P; Vezir, Ozden; Sucu, Nehir; Kibar, Deniz; Yilmaz, Sakir N; Tunctan, Bahar; Malik, Kafait U; Sahan-Firat, Seyhan.

Afiliação

Temiz-Resitoglu M; Department of Pharmacology, Faculty of Pharmacy, Mersin University, Mersin, Turkey.
Guden DS; Department of Pharmacology, Faculty of Pharmacy, Mersin University, Mersin, Turkey.
Senol SP; Department of Pharmacology, Faculty of Pharmacy, Mersin University, Mersin, Turkey.
Vezir O; Department of Cardiovascular Surgery, Mersin State Hospital, Mersin, Turkey.
Sucu N; Departments of Cardiovascular Surgery; and.
Kibar D; Histology and Embryology, Faculty of Medicine, Mersin University, Mersin, Turkey ; and.
Yilmaz SN; Histology and Embryology, Faculty of Medicine, Mersin University, Mersin, Turkey ; and.
Tunctan B; Department of Pharmacology, Faculty of Pharmacy, Mersin University, Mersin, Turkey.
Malik KU; Department of Pharmacology, College of Medicine, University of Tennessee, Center for Health Sciences, Memphis, TN.
Sahan-Firat S; Department of Pharmacology, Faculty of Pharmacy, Mersin University, Mersin, Turkey.

J Cardiovasc Pharmacol ; 79(3): 355-367, 2022 03 01.

Article em En | MEDLINE | ID: mdl-34840266

Assuntos

Acetato de Desoxicorticosterona; Hipertensão; Acetatos/efeitos adversos; Animais; Pressão Sanguínea; Acetato de Desoxicorticosterona/efeitos adversos; Hipertensão/induzido quimicamente; Hipertensão/tratamento farmacológico; Hipertensão/metabolismo; Hipertrofia; Inflamação; Masculino; Mamíferos/metabolismo; Estresse Oxidativo; Ratos; Proteína S6 Ribossômica/metabolismo; Sirolimo/efeitos adversos; Serina-Treonina Quinases TOR/metabolismo; Proteínas Quinases p38 Ativadas por Mitógeno/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Acetato de Desoxicorticosterona / Hipertensão Limite: Animals Idioma: En Revista: J Cardiovasc Pharmacol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Turquia

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