Rare Glutamic Acid Methyl Ester Peptaibols from <i>Sepedonium ampullosporum</i> Damon KSH 534 Exhibit Promising Antifungal and Anticancer Activity.

Lam, Yen T H; Ricardo, Manuel G; Rennert, Robert; Frolov, Andrej; Porzel, Andrea; Brandt, Wolfgang; Stark, Pauline; Westermann, Bernhard; Arnold, Norbert

Rare Glutamic Acid Methyl Ester Peptaibols from Sepedonium ampullosporum Damon KSH 534 Exhibit Promising Antifungal and Anticancer Activity.

Lam, Yen T H; Ricardo, Manuel G; Rennert, Robert; Frolov, Andrej; Porzel, Andrea; Brandt, Wolfgang; Stark, Pauline; Westermann, Bernhard; Arnold, Norbert.

Afiliação

Lam YTH; Department of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, D-06120 Halle (Saale), Germany.
Ricardo MG; Department of Organic Chemistry, Faculty of Chemistry, Hanoi National University of Education, Hanoi 100000, Vietnam.
Rennert R; Department of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, D-06120 Halle (Saale), Germany.
Frolov A; Department of Biomolecular Systems, Max Planck Institute of Colloids and Interfaces, D-14476 Potsdam, Germany.
Porzel A; Department of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, D-06120 Halle (Saale), Germany.
Brandt W; Department of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, D-06120 Halle (Saale), Germany.
Stark P; Department of Biochemistry, Faculty of Biology, St. Petersburg State University, 199004 St. Petersburg, Russia.
Westermann B; Department of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, D-06120 Halle (Saale), Germany.
Arnold N; Department of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, D-06120 Halle (Saale), Germany.

Int J Mol Sci ; 22(23)2021 Nov 24.

Article em En | MEDLINE | ID: mdl-34884518

Assuntos

Antifúngicos/farmacologia; Antineoplásicos/farmacologia; Ésteres/química; Ácido Glutâmico/química; Hypocreales/fisiologia; Neoplasias/tratamento farmacológico; Peptaibols/farmacologia; Ascomicetos/efeitos dos fármacos; Botrytis/efeitos dos fármacos; Humanos; Neoplasias/patologia; Peptaibols/química; Phytophthora infestans/efeitos dos fármacos; Células Tumorais Cultivadas

Palavras-chave

Sepedonium ampullosporum; ampullosporin; anticancer; antifungal; glutamic acid methyl ester; molecular docking; peptaibols; solid-phase peptide synthesis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácido Glutâmico / Ésteres / Peptaibols / Hypocreales / Antifúngicos / Neoplasias / Antineoplásicos Limite: Humans Idioma: En Revista: Int J Mol Sci Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Alemanha

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