Ileal microbial shifts after Roux-en-Y gastric bypass orchestrate changes in glucose metabolism through modulation of bile acids and L-cell adaptation.

Dang, Jerry T; Mocanu, Valentin; Park, Heekuk; Laffin, Michael; Tran, Caroline; Hotte, Naomi; Karmali, Shahzeer; Birch, Daniel W; Madsen, Karen

Dang, Jerry T; Mocanu, Valentin; Park, Heekuk; Laffin, Michael; Tran, Caroline; Hotte, Naomi; Karmali, Shahzeer; Birch, Daniel W; Madsen, Karen.

Afiliação

Dang JT; Division of General Surgery, Department of Surgery, University of Alberta Hospital, University of Alberta, 8440 112 Street NW, Edmonton, AB, T6G 2B7, Canada. dang2@ualberta.ca.
Mocanu V; Division of General Surgery, Department of Surgery, University of Alberta Hospital, University of Alberta, 8440 112 Street NW, Edmonton, AB, T6G 2B7, Canada.
Park H; Department of Medicine, Columbia University, New York City, NY, USA.
Laffin M; Division of General Surgery, Department of Surgery, University of Alberta Hospital, University of Alberta, 8440 112 Street NW, Edmonton, AB, T6G 2B7, Canada.
Tran C; Department of Biological Sciences, University of Alberta, Edmonton, AB, Canada.
Hotte N; Department of Medicine, University of Alberta, Edmonton, AB, Canada.
Karmali S; Division of General Surgery, Department of Surgery, University of Alberta Hospital, University of Alberta, 8440 112 Street NW, Edmonton, AB, T6G 2B7, Canada.
Birch DW; Division of General Surgery, Department of Surgery, University of Alberta Hospital, University of Alberta, 8440 112 Street NW, Edmonton, AB, T6G 2B7, Canada.
Madsen K; Department of Medicine, University of Alberta, Edmonton, AB, Canada.

Sci Rep ; 11(1): 23813, 2021 12 10.

Article em En | MEDLINE | ID: mdl-34893681

Assuntos

Ácidos e Sais Biliares/metabolismo; Derivação Gástrica/efeitos adversos; Microbioma Gastrointestinal; Glucose/metabolismo; Íleo/metabolismo; Íleo/microbiologia; Células L/metabolismo; Animais; Biomarcadores; Glicemia; Contagem de Células; Suscetibilidade a Doenças; Derivação Gástrica/métodos; Peptídeo 1 Semelhante ao Glucagon/metabolismo; Mucosa Intestinal/metabolismo; Mucosa Intestinal/microbiologia; Camundongos; Ratos

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácidos e Sais Biliares / Derivação Gástrica / Microbioma Gastrointestinal / Glucose / Íleo / Células L Limite: Animals Idioma: En Revista: Sci Rep Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Canadá

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