DNA methylation signatures in Blood DNA of Hutchinson-Gilford Progeria syndrome.

Bejaoui, Yosra; Razzaq, Aleem; Yousri, Noha A; Oshima, Junko; Megarbane, Andre; Qannan, Abeer; Potabattula, Ramya; Alam, Tanvir; Martin, George M; Horn, Henning F; Haaf, Thomas; Horvath, Steve; El Hajj, Nady

Bejaoui, Yosra; Razzaq, Aleem; Yousri, Noha A; Oshima, Junko; Megarbane, Andre; Qannan, Abeer; Potabattula, Ramya; Alam, Tanvir; Martin, George M; Horn, Henning F; Haaf, Thomas; Horvath, Steve; El Hajj, Nady.

Afiliação

Bejaoui Y; College of Health and Life Sciences, Qatar Foundation, Hamad Bin Khalifa University, Doha, Qatar.
Razzaq A; College of Health and Life Sciences, Qatar Foundation, Hamad Bin Khalifa University, Doha, Qatar.
Yousri NA; Genetic Medicine, Weill Cornell Medicine-Qatar, Doha, Qatar.
Oshima J; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, USA.
Megarbane A; Department of Clinical Cell Biology and Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan.
Qannan A; Department of Human Genetics, Gilbert and Rose-Marie Ghagoury School of Medicine, Lebanese American University, Byblos, Lebanon.
Potabattula R; Institut Jérôme Lejeune, Paris, France.
Alam T; College of Health and Life Sciences, Qatar Foundation, Hamad Bin Khalifa University, Doha, Qatar.
Martin GM; Institute of Human Genetics, Julius Maximilians University, Würzburg, Germany.
Horn HF; College of Science and Engineering, Hamad Bin Khalifa University, Doha, Qatar.
Haaf T; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, USA.
Horvath S; College of Health and Life Sciences, Qatar Foundation, Hamad Bin Khalifa University, Doha, Qatar.
El Hajj N; Institute of Human Genetics, Julius Maximilians University, Würzburg, Germany.

Aging Cell ; 21(2): e13555, 2022 02.

Article em En | MEDLINE | ID: mdl-35045206

Assuntos

Progéria; Síndrome de Werner; Envelhecimento/genética; DNA/genética; DNA/metabolismo; Metilação de DNA/genética; Humanos; Lamina Tipo A/genética; Lamina Tipo A/metabolismo; Mutação; Progéria/genética; Progéria/metabolismo; Síndrome de Werner/genética

Palavras-chave

DNA methylation; Hutchinson-Gilford Progeria syndrome; accelerated aging; epigenetic clock; progeroid laminopathies

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Progéria / Síndrome de Werner Limite: Humans Idioma: En Revista: Aging Cell Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Qatar

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