Bayesian two-stage design for phase II oncology trials with binary endpoint.

Chen, Lichang; Pan, Jianhong; Wu, Yanpeng; Wang, Jingxian; Chen, Fangyao; Zhao, Jun; Chen, Pingyan

Chen, Lichang; Pan, Jianhong; Wu, Yanpeng; Wang, Jingxian; Chen, Fangyao; Zhao, Jun; Chen, Pingyan.

Afiliação

Chen L; Department of Biostatistics, School of Public Health, Southern Medical University, Guangzhou, China.
Pan J; Department of Medical Statistics, School of Public Health, Sun Yat-sen University, Guangzhou, China.
Wu Y; Department of Biostatistics, School of Public Health, Southern Medical University, Guangzhou, China.
Wang J; Department of Biostatistics, School of Public Health, Southern Medical University, Guangzhou, China.
Chen F; Department of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Zhao J; Department of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Chen P; Office of Biostatistics and Clinical Pharmacology, The Center for Drug Evaluation, National Medical Products Administration, Beijing, China.

Stat Med ; 41(12): 2291-2301, 2022 05 30.

Article em En | MEDLINE | ID: mdl-35178729

Assuntos

Ensaios Clínicos Fase II como Assunto; Neoplasias; Projetos de Pesquisa; Teorema de Bayes; Humanos; Oncologia; Neoplasias/tratamento farmacológico; Probabilidade

Palavras-chave

Bayesian; Simon's two-stage design; binary endpoint; posterior probability; predictive probability

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Projetos de Pesquisa / Ensaios Clínicos Fase II como Assunto / Neoplasias Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Stat Med Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

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