Silencing of IGF2BP1 restrains ox-LDL-induced lipid accumulation and inflammation by reducing RUNX1 expression and promoting autophagy in macrophages.

Liu, Mingxin; Tao, Guizhou; Cao, Yiming; Hu, Yu; Zhang, Zhe

Liu, Mingxin; Tao, Guizhou; Cao, Yiming; Hu, Yu; Zhang, Zhe.

Afiliação

Liu M; Department of Cardiology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, P.R. China.
Tao G; Department of Cardiology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, P.R. China.
Cao Y; Department of Cardiology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, P.R. China.
Hu Y; Department of Cardiology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, P.R. China.
Zhang Z; Department of Cardiology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, P.R. China.

J Biochem Mol Toxicol ; 36(4): e22994, 2022 Apr.

Article em En | MEDLINE | ID: mdl-35179253

Assuntos

Aterosclerose; Subunidade alfa 2 de Fator de Ligação ao Core; Animais; Aterosclerose/metabolismo; Autofagia; Subunidade alfa 2 de Fator de Ligação ao Core/genética; Subunidade alfa 2 de Fator de Ligação ao Core/metabolismo; Inflamação/metabolismo; Lipoproteínas LDL/metabolismo; Macrófagos/metabolismo; Camundongos; RNA/metabolismo; RNA Mensageiro/metabolismo; Proteínas de Ligação a RNA

Palavras-chave

Runt-related transcription factor 1; atherosclerosis; autophagy; insulin-like growth factor 2 mRNA binding protein 1; macrophage

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Aterosclerose / Subunidade alfa 2 de Fator de Ligação ao Core Limite: Animals Idioma: En Revista: J Biochem Mol Toxicol Assunto da revista: BIOLOGIA MOLECULAR / BIOQUIMICA / TOXICOLOGIA Ano de publicação: 2022 Tipo de documento: Article

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