Unbiased proteomic profiling reveals the IP3R modulator AHCYL1/IRBIT as a novel interactor of microtubule-associated protein tau.

Wischhof, Lena; Adhikari, Aasha; Mondal, Mrityunjoy; Marsal-Cots, Anaïs; Biernat, Jacek; Mandelkow, Eva Maria; Mandelkow, Eckhard; Ehninger, Dan; Nicotera, Pierluigi; Bano, Daniele

Wischhof, Lena; Adhikari, Aasha; Mondal, Mrityunjoy; Marsal-Cots, Anaïs; Biernat, Jacek; Mandelkow, Eva Maria; Mandelkow, Eckhard; Ehninger, Dan; Nicotera, Pierluigi; Bano, Daniele.

Afiliação

Wischhof L; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Adhikari A; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Mondal M; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Marsal-Cots A; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Biernat J; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany; CAESAR Research Center, Bonn, Germany.
Mandelkow EM; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany; CAESAR Research Center, Bonn, Germany.
Mandelkow E; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany; CAESAR Research Center, Bonn, Germany; Department of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn, Bonn, Germany.
Ehninger D; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Nicotera P; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Bano D; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany. Electronic address: daniele.bano@dzne.de.

J Biol Chem ; 298(4): 101774, 2022 04.

Article em En | MEDLINE | ID: mdl-35218773

Assuntos

Lectinas Tipo C; Proteínas de Membrana; Proteômica; Proteínas tau; Retículo Endoplasmático/genética; Retículo Endoplasmático/metabolismo; Expressão Gênica; Humanos; Lectinas Tipo C/genética; Lectinas Tipo C/metabolismo; Proteínas de Membrana/genética; Proteínas de Membrana/metabolismo; Ligação Proteica; Proteínas tau/genética; Proteínas tau/metabolismo

Palavras-chave

Alzheimer's disease; SAH hydrolaselike protein 1 (AHCYL1/IRBIT); autophagy; human protein microarray; microtubule-associated protein tau

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas tau / Lectinas Tipo C / Proteômica / Proteínas de Membrana Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Alemanha

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