Macrophage-targeting gene silencing orchestrates myocardial microenvironment remodeling toward the anti-inflammatory treatment of ischemia-reperfusion (IR) injury.

Wang, Yao; Hou, Mengying; Duan, Shanzhou; Zhao, Ziyin; Wu, Xuejie; Chen, Yongbing; Yin, Lichen

Wang, Yao; Hou, Mengying; Duan, Shanzhou; Zhao, Ziyin; Wu, Xuejie; Chen, Yongbing; Yin, Lichen.

Afiliação

Wang Y; Department of Cardiothoracic Surgery, the Second Affiliated Hospital of Soochow University, Suzhou, 215002, China.
Hou M; Institute of Functional Nano and Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Soochow University, Suzhou, 215123, China.
Duan S; Yancheng First Hospital, Affiliated Hospital of Nanjing University Medical School, Yancheng, 224005, China.
Zhao Z; Institute of Functional Nano and Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Soochow University, Suzhou, 215123, China.
Wu X; Department of Cardiothoracic Surgery, the Second Affiliated Hospital of Soochow University, Suzhou, 215002, China.
Chen Y; Institute of Functional Nano and Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Soochow University, Suzhou, 215123, China.
Yin L; Department of Cardiothoracic Surgery, the Second Affiliated Hospital of Soochow University, Suzhou, 215002, China.

Bioact Mater ; 17: 320-333, 2022 Nov.

Article em En | MEDLINE | ID: mdl-35386446

Palavras-chave

Anti-inflammation; Microenvironment remodeling; Myocardial ischemia-reperfusion (IR) injury; Reduction-responsive branched poly(ß-amino ester); siRNA/miRNA delivery

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Bioact Mater Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

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