Your browser doesn't support javascript.
loading
Donor substance abuse and heart transplantation outcomes.
Sabra, Mohammad; Ilonze, Onyedika; Rao, Roopa A; Saleem, Kashif; Guglin, Maya E.
Afiliação
  • Sabra M; Department of Internal Medicine, Indiana University School of Medicine, IN, Indinapolis, USA. mohammadsabra93@gmail.com.
  • Ilonze O; Indiana University School of Medicine, Krannert Institute of Cardiology, Indianapolis, IN, USA.
  • Rao RA; Indiana University School of Medicine, Krannert Institute of Cardiology, Indianapolis, IN, USA.
  • Saleem K; Indiana University School of Medicine, Krannert Institute of Cardiology, Indianapolis, IN, USA.
  • Guglin ME; Indiana University School of Medicine, Krannert Institute of Cardiology, Indianapolis, IN, USA.
Heart Fail Rev ; 28(1): 207-215, 2023 01.
Article em En | MEDLINE | ID: mdl-35435527
Heart failure continues to account for millions of cases and deaths worldwide. Heart transplant is the gold standard for treatment of advanced heart failure. Unfortunately, the supply of donor hearts continues to be limited with the increase in demand for heart transplantation. In this review, we aim to explore the safety and efficacy of using hearts from donors with history of substance use. Despite the theoretical effect of cocaine and alcohol on the cardiovascular system, several studies demonstrate no difference in outcomes (overall survival, graft rejection, graft vasculopathy) when using hearts from patients with history of cocaine and alcohol use. The opioid epidemic has expanded the potential donor pool where the current studies have not shown any adverse outcomes when considering donors with history of opioid use. The currently available evidence would support the use of donor hearts from patients with history of alcohol, cocaine, opioids, and marijuana use. Further studies are needed to evaluate the safety of using donor hearts from patients with history of nicotine use.
Assuntos
Palavras-chave

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transplante de Coração / Cocaína / Transtornos Relacionados ao Uso de Substâncias / Insuficiência Cardíaca Limite: Humans Idioma: En Revista: Heart Fail Rev Assunto da revista: CARDIOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transplante de Coração / Cocaína / Transtornos Relacionados ao Uso de Substâncias / Insuficiência Cardíaca Limite: Humans Idioma: En Revista: Heart Fail Rev Assunto da revista: CARDIOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos