Mir-675-5p supports hypoxia-induced drug resistance in colorectal cancer cells.

Zichittella, Chiara; Barreca, Maria Magdalena; Cordaro, Aurora; Corrado, Chiara; Alessandro, Riccardo; Conigliaro, Alice

Zichittella, Chiara; Barreca, Maria Magdalena; Cordaro, Aurora; Corrado, Chiara; Alessandro, Riccardo; Conigliaro, Alice.

Afiliação

Zichittella C; Department of Biomedicine, Neuroscience and Advanced Diagnostics (Bi.N.D.), Section of Biology and Genetics, University of Palermo, 90133, Palermo, Italy.
Barreca MM; Department of Biomedicine, Neuroscience and Advanced Diagnostics (Bi.N.D.), Section of Biology and Genetics, University of Palermo, 90133, Palermo, Italy.
Cordaro A; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, 90128, Palermo, Italy.
Corrado C; Department of Biomedicine, Neuroscience and Advanced Diagnostics (Bi.N.D.), Section of Biology and Genetics, University of Palermo, 90133, Palermo, Italy.
Alessandro R; Department of Biomedicine, Neuroscience and Advanced Diagnostics (Bi.N.D.), Section of Biology and Genetics, University of Palermo, 90133, Palermo, Italy.
Conigliaro A; Department of Biomedicine, Neuroscience and Advanced Diagnostics (Bi.N.D.), Section of Biology and Genetics, University of Palermo, 90133, Palermo, Italy.

BMC Cancer ; 22(1): 567, 2022 May 20.

Article em En | MEDLINE | ID: mdl-35596172

Assuntos

Neoplasias Colorretais; Resistencia a Medicamentos Antineoplásicos; MicroRNAs; Apoptose/genética; Caspase 3/metabolismo; Linhagem Celular Tumoral; Neoplasias Colorretais/tratamento farmacológico; Neoplasias Colorretais/genética; Neoplasias Colorretais/metabolismo; Resistencia a Medicamentos Antineoplásicos/genética; Fluoruracila/farmacologia; Fluoruracila/uso terapêutico; Regulação Neoplásica da Expressão Gênica; Humanos; Hipóxia/genética; Hipóxia/metabolismo; MicroRNAs/genética; MicroRNAs/metabolismo

Palavras-chave

5-fluorouracil (5-FU); Apoptosis; Colorectal cancer (CRC); Drug resistance; Hypoxia; MicroRNA

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Resistencia a Medicamentos Antineoplásicos / MicroRNAs Limite: Humans Idioma: En Revista: BMC Cancer Assunto da revista: NEOPLASIAS Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Itália

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