<i>Asparagus falcatus</i> L. (Asparagaceae) leaf extracts attenuate doxorubicin-induced renal toxicity via antioxidant, anti-inflammatory, and anti-apoptotic pathways.

Amarasiri, Sachinthi S; Attanayake, Anoja P; Mudduwa, Lakmini K B; Jayatilaka, Kamani A P W

Asparagus falcatus L. (Asparagaceae) leaf extracts attenuate doxorubicin-induced renal toxicity via antioxidant, anti-inflammatory, and anti-apoptotic pathways.

Amarasiri, Sachinthi S; Attanayake, Anoja P; Mudduwa, Lakmini K B; Jayatilaka, Kamani A P W.

Afiliação

Amarasiri SS; Department of Medical Laboratory Science, Faculty of Allied Health Sciences, University of Ruhuna, Galle, Sri Lanka.
Attanayake AP; Department of Biochemistry, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.
Mudduwa LKB; Department of Pathology, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.
Jayatilaka KAPW; Department of Biochemistry, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.

Drug Chem Toxicol ; 46(4): 677-691, 2023 Nov.

Article em En | MEDLINE | ID: mdl-35637614

Assuntos

Antioxidantes; Asparagaceae; Ratos; Animais; Antioxidantes/farmacologia; Antioxidantes/metabolismo; Ratos Wistar; Hexanos/metabolismo; Hexanos/farmacologia; Rim/patologia; Asparagaceae/metabolismo; Estresse Oxidativo; Doxorrubicina/toxicidade; Anti-Inflamatórios/farmacologia; Butanóis; Extratos Vegetais/farmacologia; Extratos Vegetais/metabolismo

Palavras-chave

Anti-apoptotic effects; Asparagus falcatus; anti-inflammatory effects; antioxidant potential; doxorubicin; renal toxicity

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Asparagaceae / Antioxidantes Limite: Animals Idioma: En Revista: Drug Chem Toxicol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Sri Lanka

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