Inhibition of vascular endothelial growth factor alleviates neovascular retinopathy with regulated neurotrophic/proinflammatory cytokines through the modulation of DBI-TSPO signaling.

Gao, Shuang; Li, Na; Wang, Yanuo; Lin, Zhongjing; Zhu, Yanji; Xu, Jianmin; Zhang, Qiong; Zhu, Caihong; Zhou, Yingming; Zhou, Jia; Shen, Xi

Gao, Shuang; Li, Na; Wang, Yanuo; Lin, Zhongjing; Zhu, Yanji; Xu, Jianmin; Zhang, Qiong; Zhu, Caihong; Zhou, Yingming; Zhou, Jia; Shen, Xi.

Afiliação

Gao S; Department of Ophthalmology, Ruijin Hospital, Affiliated Shanghai Jiaotong University School of Medicine, Shanghai, China.
Li N; Department of Ophthalmology, Ruijin Hospital, Affiliated Shanghai Jiaotong University School of Medicine, Shanghai, China.
Wang Y; Department of Ophthalmology, Ruijin Hospital, Affiliated Shanghai Jiaotong University School of Medicine, Shanghai, China.
Lin Z; Department of Ophthalmology, Renji Hospital, Affiliated Shanghai Jiaotong University School of Medicine, Shanghai, China.
Zhu Y; Department of Ophthalmology, Ruijin Hospital, Affiliated Shanghai Jiaotong University School of Medicine, Shanghai, China.
Xu J; Department of Ophthalmology, Ruijin Hospital, Affiliated Shanghai Jiaotong University School of Medicine, Shanghai, China.
Zhang Q; Department of Ophthalmology, Ruijin Hospital, Affiliated Shanghai Jiaotong University School of Medicine, Shanghai, China.
Zhu C; Department of Ophthalmology, Ruijin Hospital, Affiliated Shanghai Jiaotong University School of Medicine, Shanghai, China.
Zhou Y; Department of Ophthalmology, Ruijin Hospital, Affiliated Shanghai Jiaotong University School of Medicine, Shanghai, China.
Zhou J; Department of Ophthalmology, Ruijin Hospital, LuWan Branch, Affiliated Shanghai Jiaotong University School of Medicine, Shanghai, China.
Shen X; Department of Ophthalmology, Ruijin Hospital, Affiliated Shanghai Jiaotong University School of Medicine, Shanghai, China.

FASEB J ; 36(7): e22367, 2022 07.

Article em En | MEDLINE | ID: mdl-35639422

Assuntos

Citocinas; Retinopatia Diabética; Animais; Humanos; Camundongos; Citocinas/metabolismo; Retinopatia Diabética/tratamento farmacológico; Retinopatia Diabética/metabolismo; Inibidor da Ligação a Diazepam/metabolismo; Inflamação/tratamento farmacológico; Inflamação/metabolismo; Fator de Crescimento Neural/metabolismo; Receptores de GABA/metabolismo; Transdução de Sinais; Fator A de Crescimento do Endotélio Vascular/genética; Fator A de Crescimento do Endotélio Vascular/metabolismo; Corpo Vítreo/metabolismo

Palavras-chave

Müller cell; diazepam binding inhibitor; microglial cell; translocator protein (18 kDa); vascular endothelial growth factor

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Citocinas / Retinopatia Diabética Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: FASEB J Assunto da revista: BIOLOGIA / FISIOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

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