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Phase IIa, randomised, double-blind study of GSK3389404 in patients with chronic hepatitis B on stable nucleos(t)ide therapy.
Yuen, Man-Fung; Heo, Jeong; Kumada, Hiromitsu; Suzuki, Fumitaka; Suzuki, Yoshiyuki; Xie, Qing; Jia, Jidong; Karino, Yoshiyasu; Hou, Jinlin; Chayama, Kazuaki; Imamura, Michio; Lao-Tan, Judy Y; Lim, Seng Gee; Tanaka, Yasuhito; Xie, Wen; Yoon, Jung-Hwan; Duan, Zhongping; Kurosaki, Masayuki; Park, Sung-Jae; Labio, Madalinee Eternity; Kumar, Rajneesh; Kweon, Young-Oh; Yim, Hyung Joon; Tao, Yu; Cremer, Jennifer; Elston, Robert; Davies, Matt; Baptiste-Brown, Sharon; Han, Kelong; Campbell, Fiona M; Paff, Melanie; Theodore, Dickens.
Afiliação
  • Yuen MF; Department of Medicine and State Key Laboratory of Liver Research, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China. Electronic address: mfyuen@hku.hk.
  • Heo J; Department of Internal Medicine, College of Medicine, Pusan National University, and Biomedical Research Institute, Pusan National University Hospital, Busan, Republic of Korea.
  • Kumada H; Department of Hepatology, Toranomon Hospital Kajigaya, Kanagawa, Japan.
  • Suzuki F; Department of Hepatology, Toranomon Hospital Kajigaya, Kanagawa, Japan.
  • Suzuki Y; Department of Hepatology, Toranomon Hospital, Tokyo, Japan.
  • Xie Q; Department of Infectious Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
  • Jia J; Liver Research Center, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
  • Karino Y; Department of Hepatology, Hokkaido P.W.F.a.C. Sapporo-Kosei General Hospital, Hokkaido, Japan.
  • Hou J; Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou, China.
  • Chayama K; Collaborative Research Laboratory of Medical Innovation, Hiroshima University, Hiroshima, Japan; Research Center for Hepatology and Gastroenterology, Hiroshima University, Hiroshima, Japan; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
  • Imamura M; Department of Gastroenterology and Metabolism, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
  • Lao-Tan JY; Gastroenterology, Cebu Doctors University Hospital, Cebu, Philippines.
  • Lim SG; Division of Gastroenterology & Hepatology, Department of Medicine, National University Health System, Singapore.
  • Tanaka Y; Department of Virology and Liver Unit, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
  • Xie W; Center of Liver Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
  • Yoon JH; Department of Internal Medicine and Liver Research Institute, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
  • Duan Z; Artifical Liver Center, Beijing Youan Hospital, Capital Medical University, Beijing, China.
  • Kurosaki M; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.
  • Park SJ; Department of Gastroenterology and Hepatology, Inje University Busan Paik Hospital, Busan, Republic of Korea.
  • Labio ME; Section of Gastroenterology and Hepatology, Department of Medicine, Makati Medical Center, Makati, Philippines.
  • Kumar R; Department of Gastroenterology and Hepatology, Singapore General Hospital, Singapore.
  • Kweon YO; Division of Gastroenterology and Hepatology, Kyungpook National University Hospital, Daegu, Republic of Korea.
  • Yim HJ; Department of Internal Medicine, Korea University Ansan Hospital, Ansan, Republic of Korea.
  • Tao Y; R&D Projects Clinical Platforms and Sciences, GSK, Collegeville, PA, USA.
  • Cremer J; Hepatology GI Clinical Sciences, GSK, NC, USA.
  • Elston R; Hepatology GI Clinical Sciences, GSK, Hertfordshire, UK.
  • Davies M; Global Safety, GSK, Brentford, UK.
  • Baptiste-Brown S; R&D Global Medical Affairs, GSK, PA, USA.
  • Han K; Clinical Pharmacology Modeling & Simulation, GSK, PA, USA.
  • Campbell FM; Hepatology GI Clinical Sciences, GSK, Hertfordshire, UK.
  • Paff M; Medicine Development Leaders, GSK, PA, USA.
  • Theodore D; Hepatology GI Clinical Sciences, GSK, NC, USA.
J Hepatol ; 77(4): 967-977, 2022 10.
Article em En | MEDLINE | ID: mdl-35714812
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hepatite B Crônica Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Humans Idioma: En Revista: J Hepatol Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hepatite B Crônica Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Humans Idioma: En Revista: J Hepatol Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2022 Tipo de documento: Article