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Inhaled siRNA nanoparticles targeting IL11 inhibit lung fibrosis and improve pulmonary function post-bleomycin challenge.
Bai, Xin; Zhao, Guolin; Chen, Qijing; Li, Zhongyu; Gao, Mingzhu; Ho, William; Xu, Xiaoyang; Zhang, Xue-Qing.
Afiliação
  • Bai X; Engineering Research Center of Cell and Therapeutic Antibody, Ministry of Education, and School of Pharmacy, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, PR China.
  • Zhao G; Engineering Research Center of Cell and Therapeutic Antibody, Ministry of Education, and School of Pharmacy, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, PR China.
  • Chen Q; Engineering Research Center of Cell and Therapeutic Antibody, Ministry of Education, and School of Pharmacy, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, PR China.
  • Li Z; Department of Chemical and Materials Engineering, New Jersey Institute of Technology, Newark, NJ 07102, USA.
  • Gao M; Engineering Research Center of Cell and Therapeutic Antibody, Ministry of Education, and School of Pharmacy, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, PR China.
  • Ho W; Department of Chemical and Materials Engineering, New Jersey Institute of Technology, Newark, NJ 07102, USA.
  • Xu X; Department of Chemical and Materials Engineering, New Jersey Institute of Technology, Newark, NJ 07102, USA.
  • Zhang XQ; Department of Biomedical Engineering, New Jersey Institute of Technology, Newark, NJ 07102, USA.
Sci Adv ; 8(25): eabn7162, 2022 06 24.
Article em En | MEDLINE | ID: mdl-35731866
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Nanopartículas / Fibrose Pulmonar Idiopática Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Sci Adv Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Nanopartículas / Fibrose Pulmonar Idiopática Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Sci Adv Ano de publicação: 2022 Tipo de documento: Article