[Comparison of 2 methods of measuring microalbuminuria. Immunonephelometry and radioimmunology]. / Comparaison de deux méthodes de dosage de la microalbuminurie. L'immunonéphélémétrie et la radioimmunologie.
Ann Biol Clin (Paris)
; 45(1): 78-84, 1987.
Article
em Fr
| MEDLINE
| ID: mdl-3578939
ABSTRACT
The early detection of microalbuminuria in insulin dependent diabetes is considered as a sign of initial stage of nephropathy (possibly reversible if glycemic balance is well maintained). This detection requires very accurate methods as radioimmunoassays. Yet, they are so slow that they represent an obstacle to systematic detection. We report an appraisement of an immunonephelemetric method. Results reveal that immunonephelemetry is a sensitive and accurate method (threshold of sensitivity 0.5 mg/l; CV intra assay less than 5%; CV inter assays less than 10%; analytical recovery 94-104%). Moreover, immunonephelemetry and radioimmunology are significantly well correlated (r = 0.977, p less than 0.001). As a conclusion, we can say that thanks to complete automation, immunonephelemetry is a choice method to test great lines of samples.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Albuminúria
Tipo de estudo:
Screening_studies
Limite:
Humans
Idioma:
Fr
Revista:
Ann Biol Clin (Paris)
Ano de publicação:
1987
Tipo de documento:
Article