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Corneal thinning following bevacizumab intrastromal injection for the treatment of idiopathic lipid keratopathy.
Sun, Kristie J; Jun, Albert S; Bohm, Kelley; Daroszewski, Daniel; Jabbour, Samir.
Afiliação
  • Sun KJ; Case Western Reserve University School of Medicine, 9501 Euclid Ave, Cleveland, OH, USA, 44106.
  • Jun AS; The Johns Hopkins Wilmer Eye Institute, 1800 Orleans St, Baltimore, MD, USA, 21287.
  • Bohm K; The Johns Hopkins Wilmer Eye Institute, 1800 Orleans St, Baltimore, MD, USA, 21287.
  • Daroszewski D; The Johns Hopkins Wilmer Eye Institute, 1800 Orleans St, Baltimore, MD, USA, 21287.
  • Jabbour S; The Johns Hopkins Wilmer Eye Institute, 1800 Orleans St, Baltimore, MD, USA, 21287.
Am J Ophthalmol Case Rep ; 27: 101618, 2022 Sep.
Article em En | MEDLINE | ID: mdl-35800403
Purpose: To describe the occurrence of corneal thinning in a patient following intrastromal injection of bevacizumab to treat lipid keratopathy. Observations: A 36-year-old female presented with decreased vision in her right eye with central posterior corneal haze and underwent a treatment regimen including artificial tears, cyclosporine 0.05% drops, prednisolone 1% and oral Valacyclovir 1g with no improvement. Neovascularization was noted at 18 months follow up and treated with intrastromal bevacizumab injections at 24 months. The feeder vessel was attenuated at 3- and 6-months post-injection, but tomography indicated sustained thinning and flattening of the cornea at the injection site contributing to the development of irregular astigmatism. Conclusions and Importance: Corneal thinning is an uncommon potential side effect of intrastromal bevacizumab injection that may affect postoperative visual acuity.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Am J Ophthalmol Case Rep Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Am J Ophthalmol Case Rep Ano de publicação: 2022 Tipo de documento: Article