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QTQTN motif upstream of the furin-cleavage site plays a key role in SARS-CoV-2 infection and pathogenesis.
Vu, Michelle N; Lokugamage, Kumari G; Plante, Jessica A; Scharton, Dionna; Bailey, Aaron O; Sotcheff, Stephanea; Swetnam, Daniele M; Johnson, Bryan A; Schindewolf, Craig; Alvarado, R Elias; Crocquet-Valdes, Patricia A; Debbink, Kari; Weaver, Scott C; Walker, David H; Russell, William K; Routh, Andrew L; Plante, Kenneth S; Menachery, Vineet D.
Afiliação
  • Vu MN; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555.
  • Lokugamage KG; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555.
  • Plante JA; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555.
  • Scharton D; Institute for Human Infection and Immunity, University of Texas Medical Branch, Galveston, TX 77555.
  • Bailey AO; World Reference Center of Emerging Viruses and Arboviruses, University of Texas Medical Branch, Galveston, TX 77555.
  • Sotcheff S; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555.
  • Swetnam DM; Institute for Human Infection and Immunity, University of Texas Medical Branch, Galveston, TX 77555.
  • Johnson BA; World Reference Center of Emerging Viruses and Arboviruses, University of Texas Medical Branch, Galveston, TX 77555.
  • Schindewolf C; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555.
  • Alvarado RE; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555.
  • Crocquet-Valdes PA; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555.
  • Debbink K; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555.
  • Weaver SC; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555.
  • Walker DH; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555.
  • Russell WK; Institute for Translational Sciences, University of Texas Medical Branch, Galveston, TX.
  • Routh AL; Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555.
  • Plante KS; Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21211.
  • Menachery VD; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555.
Proc Natl Acad Sci U S A ; 119(32): e2205690119, 2022 08 09.
Article em En | MEDLINE | ID: mdl-35881779
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Furina / Proteólise / Glicoproteína da Espícula de Coronavírus / SARS-CoV-2 / COVID-19 Tipo de estudo: Etiology_studies Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Furina / Proteólise / Glicoproteína da Espícula de Coronavírus / SARS-CoV-2 / COVID-19 Tipo de estudo: Etiology_studies Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2022 Tipo de documento: Article