Molecular insights into the regulation of constitutive activity by RNA editing of 5HT<sub>2C</sub> serotonin receptors.

Gumpper, Ryan H; Fay, Jonathan F; Roth, Bryan L

Molecular insights into the regulation of constitutive activity by RNA editing of 5HT_2C serotonin receptors.

Gumpper, Ryan H; Fay, Jonathan F; Roth, Bryan L.

Afiliação

Gumpper RH; Department of Pharmacology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599, USA. Electronic address: rgumpper@email.unc.edu.
Fay JF; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599, USA.
Roth BL; Department of Pharmacology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599, USA. Electronic address: bryan_roth@med.unc.edu.

Cell Rep ; 40(7): 111211, 2022 08 16.

Article em En | MEDLINE | ID: mdl-35977511

Assuntos

Edição de RNA; Receptores de Serotonina; Isoformas de Proteínas/genética; Isoformas de Proteínas/metabolismo; RNA Mensageiro/genética; RNA Mensageiro/metabolismo; Receptores de Serotonina/metabolismo; Transdução de Sinais/genética

Palavras-chave

5HT(2C)R; CP: Molecular biology; G-protein-coupled receptor; Gq protein; constitutive activity; lorcaserin; psilocin; serotonin; structural biology

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de Serotonina / Edição de RNA Idioma: En Revista: Cell Rep Ano de publicação: 2022 Tipo de documento: Article

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