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Eprenetapopt triggers ferroptosis, inhibits NFS1 cysteine desulfurase, and synergizes with serine and glycine dietary restriction.
Fujihara, Kenji M; Zhang, Bonnie Z; Jackson, Thomas D; Ogunkola, Moses O; Nijagal, Brunda; Milne, Julia V; Sallman, David A; Ang, Ching-Seng; Nikolic, Iva; Kearney, Conor J; Hogg, Simon J; Cabalag, Carlos S; Sutton, Vivien R; Watt, Sally; Fujihara, Asuka T; Trapani, Joseph A; Simpson, Kaylene J; Stojanovski, Diana; Leimkühler, Silke; Haupt, Sue; Phillips, Wayne A; Clemons, Nicholas J.
Afiliação
  • Fujihara KM; Gastrointestinal Cancer Program, Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
  • Zhang BZ; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.
  • Jackson TD; Gastrointestinal Cancer Program, Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
  • Ogunkola MO; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.
  • Nijagal B; Department of Biochemistry and Pharmacology, The University of Melbourne, Parkville, Victoria, Australia.
  • Milne JV; Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria, Australia.
  • Sallman DA; Institute of Biochemistry and Biology Department for Molecular Enzymology, University of Potsdam, Potsdam, Germany.
  • Ang CS; Metabolomics Australia, The Bio21 Institute of Molecular Science and Biotechnology, The University of Melbourne, Parkville, Victoria, Australia.
  • Nikolic I; Gastrointestinal Cancer Program, Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
  • Kearney CJ; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.
  • Hogg SJ; Malignant Hematology Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.
  • Cabalag CS; Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria, Australia.
  • Sutton VR; Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
  • Watt S; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.
  • Fujihara AT; Translational Hematology Program, Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
  • Trapani JA; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.
  • Simpson KJ; Translational Hematology Program, Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
  • Stojanovski D; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Leimkühler S; Gastrointestinal Cancer Program, Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
  • Haupt S; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.
  • Phillips WA; Department of Surgical Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
  • Clemons NJ; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.
Sci Adv ; 8(37): eabm9427, 2022 Sep 16.
Article em En | MEDLINE | ID: mdl-36103522
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Sci Adv Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Austrália
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Sci Adv Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Austrália