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Robust deep learning-based protein sequence design using ProteinMPNN.
Dauparas, J; Anishchenko, I; Bennett, N; Bai, H; Ragotte, R J; Milles, L F; Wicky, B I M; Courbet, A; de Haas, R J; Bethel, N; Leung, P J Y; Huddy, T F; Pellock, S; Tischer, D; Chan, F; Koepnick, B; Nguyen, H; Kang, A; Sankaran, B; Bera, A K; King, N P; Baker, D.
Afiliação
  • Dauparas J; Department of Biochemistry, University of Washington, Seattle, WA, USA.
  • Anishchenko I; Institute for Protein Design, University of Washington, Seattle, WA, USA.
  • Bennett N; Department of Biochemistry, University of Washington, Seattle, WA, USA.
  • Bai H; Institute for Protein Design, University of Washington, Seattle, WA, USA.
  • Ragotte RJ; Department of Biochemistry, University of Washington, Seattle, WA, USA.
  • Milles LF; Institute for Protein Design, University of Washington, Seattle, WA, USA.
  • Wicky BIM; Molecular Engineering Graduate Program, University of Washington, Seattle, WA, USA.
  • Courbet A; Department of Biochemistry, University of Washington, Seattle, WA, USA.
  • de Haas RJ; Institute for Protein Design, University of Washington, Seattle, WA, USA.
  • Bethel N; Howard Hughes Medical Institute, University of Washington, Seattle, WA, USA.
  • Leung PJY; Department of Biochemistry, University of Washington, Seattle, WA, USA.
  • Huddy TF; Institute for Protein Design, University of Washington, Seattle, WA, USA.
  • Pellock S; Department of Biochemistry, University of Washington, Seattle, WA, USA.
  • Tischer D; Institute for Protein Design, University of Washington, Seattle, WA, USA.
  • Chan F; Department of Biochemistry, University of Washington, Seattle, WA, USA.
  • Koepnick B; Institute for Protein Design, University of Washington, Seattle, WA, USA.
  • Nguyen H; Department of Biochemistry, University of Washington, Seattle, WA, USA.
  • Kang A; Institute for Protein Design, University of Washington, Seattle, WA, USA.
  • Sankaran B; Howard Hughes Medical Institute, University of Washington, Seattle, WA, USA.
  • Bera AK; Department of Physical Chemistry and Soft Matter, Wageningen University and Research, Wageningen, Netherlands.
  • King NP; Department of Biochemistry, University of Washington, Seattle, WA, USA.
  • Baker D; Institute for Protein Design, University of Washington, Seattle, WA, USA.
Science ; 378(6615): 49-56, 2022 10 07.
Article em En | MEDLINE | ID: mdl-36108050
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Engenharia de Proteínas / Proteínas / Aprendizado Profundo Idioma: En Revista: Science Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Engenharia de Proteínas / Proteínas / Aprendizado Profundo Idioma: En Revista: Science Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos