Fibroblast-derived CXCL12 increases vascular permeability in a 3-D microfluidic model independent of extracellular matrix contractility.

Holter, Jacob C; Chang, Chia-Wen; Avendano, Alex; Garg, Ayush A; Verma, Ajeet K; Charan, Manish; Ahirwar, Dinesh K; Ganju, Ramesh K; Song, Jonathan W

Holter, Jacob C; Chang, Chia-Wen; Avendano, Alex; Garg, Ayush A; Verma, Ajeet K; Charan, Manish; Ahirwar, Dinesh K; Ganju, Ramesh K; Song, Jonathan W.

Afiliação

Holter JC; Department of Biomedical Engineering, The Ohio State University, Columbus, OH, United States.
Chang CW; Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH, United States.
Avendano A; Department of Biomedical Engineering, The Ohio State University, Columbus, OH, United States.
Garg AA; Department of Mechanical and Aerospace Engineering, The Ohio State University, Columbus, OH, United States.
Verma AK; Department of Pathology, College of Medicine, The Ohio State University, Columbus, OH, United States.
Charan M; Comprehensive Cancer Center, The Ohio State University, Columbus, OH, United States.
Ahirwar DK; Department of Pathology, College of Medicine, The Ohio State University, Columbus, OH, United States.
Ganju RK; Department of Pathology, College of Medicine, The Ohio State University, Columbus, OH, United States.
Song JW; Department of Bioscience and Bioengineering, Indian Institute of Technology, Jodhpur, RJ, India.

Front Bioeng Biotechnol ; 10: 888431, 2022.

Article em En | MEDLINE | ID: mdl-36118583

Palavras-chave

cancer-associated fibroblast; collagen hydrogel; microfluidics; microtissue analogue; paracrine signaling; tumor microenvironment

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Front Bioeng Biotechnol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

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