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Discovery, Characterization, and Structure-Based Optimization of Small-Molecule In Vitro and In Vivo Probes for Human DNA Polymerase Theta.
Stockley, Martin L; Ferdinand, Amanda; Benedetti, Giovanni; Blencowe, Peter; Boyd, Susan M; Calder, Mat; Charles, Mark D; Edwardes, Lucy V; Ekwuru, Tennyson; Finch, Harry; Galbiati, Alessandro; Geo, Lerin; Grande, Diego; Grinkevich, Vera; Holliday, Nicholas D; Krajewski, Wojciech W; MacDonald, Ellen; Majithiya, Jayesh B; McCarron, Hollie; McWhirter, Claire L; Patel, Viral; Pedder, Chris; Rajendra, Eeson; Ranzani, Marco; Rigoreau, Laurent J M; Robinson, Helen M R; Schaedler, Theresia; Sirina, Julija; Smith, Graeme C M; Swarbrick, Martin E; Turnbull, Andrew P; Willis, Simon; Heald, Robert A.
Afiliação
  • Stockley ML; Artios Pharma Ltd., B940, Babraham Research Campus, CambridgeCB22 3FH, U. K.
  • Ferdinand A; Cancer Research Horizons Therapeutic Innovation, Jonas Webb Building, Babraham Research Campus, CambridgeCB22 3AT, U. K.
  • Benedetti G; Artios Pharma Ltd., B940, Babraham Research Campus, CambridgeCB22 3FH, U. K.
  • Blencowe P; Cancer Research Horizons Therapeutic Innovation, Jonas Webb Building, Babraham Research Campus, CambridgeCB22 3AT, U. K.
  • Boyd SM; CompChem Solutions Ltd, St John's Innovation Centre, Cowley Rd, CambridgeCB4 0WS, U. K.
  • Calder M; Cancer Research Horizons Therapeutic Innovation, Jonas Webb Building, Babraham Research Campus, CambridgeCB22 3AT, U. K.
  • Charles MD; Cancer Research Horizons Therapeutic Innovation, Jonas Webb Building, Babraham Research Campus, CambridgeCB22 3AT, U. K.
  • Edwardes LV; Artios Pharma Ltd., B940, Babraham Research Campus, CambridgeCB22 3FH, U. K.
  • Ekwuru T; Cancer Research Horizons Therapeutic Innovation, Jonas Webb Building, Babraham Research Campus, CambridgeCB22 3AT, U. K.
  • Finch H; Artios Pharma Ltd., B940, Babraham Research Campus, CambridgeCB22 3FH, U. K.
  • Galbiati A; Artios Pharma Ltd., B940, Babraham Research Campus, CambridgeCB22 3FH, U. K.
  • Geo L; Artios Pharma Ltd., B940, Babraham Research Campus, CambridgeCB22 3FH, U. K.
  • Grande D; Artios Pharma Ltd., B940, Babraham Research Campus, CambridgeCB22 3FH, U. K.
  • Grinkevich V; Artios Pharma Ltd., B940, Babraham Research Campus, CambridgeCB22 3FH, U. K.
  • Holliday ND; Excellerate Bioscience Ltd., BioCity, Pennyfoot Street, NottinghamNG1 1GF, U. K.
  • Krajewski WW; Cancer Research Horizons Therapeutic Innovation, The Francis Crick Institute, 1 Midland Road, LondonNW1 1AT, U. K.
  • MacDonald E; Cancer Research Horizons Therapeutic Innovation, Jonas Webb Building, Babraham Research Campus, CambridgeCB22 3AT, U. K.
  • Majithiya JB; Artios Pharma Ltd., B940, Babraham Research Campus, CambridgeCB22 3FH, U. K.
  • McCarron H; Cancer Research Horizons Therapeutic Innovation, Jonas Webb Building, Babraham Research Campus, CambridgeCB22 3AT, U. K.
  • McWhirter CL; Artios Pharma Ltd., B940, Babraham Research Campus, CambridgeCB22 3FH, U. K.
  • Patel V; Excellerate Bioscience Ltd., BioCity, Pennyfoot Street, NottinghamNG1 1GF, U. K.
  • Pedder C; Cancer Research Horizons Therapeutic Innovation, Jonas Webb Building, Babraham Research Campus, CambridgeCB22 3AT, U. K.
  • Rajendra E; Artios Pharma Ltd., B940, Babraham Research Campus, CambridgeCB22 3FH, U. K.
  • Ranzani M; Artios Pharma Ltd., B940, Babraham Research Campus, CambridgeCB22 3FH, U. K.
  • Rigoreau LJM; Cancer Research Horizons Therapeutic Innovation, Jonas Webb Building, Babraham Research Campus, CambridgeCB22 3AT, U. K.
  • Robinson HMR; Artios Pharma Ltd., B940, Babraham Research Campus, CambridgeCB22 3FH, U. K.
  • Schaedler T; Artios Pharma Ltd., B940, Babraham Research Campus, CambridgeCB22 3FH, U. K.
  • Sirina J; Excellerate Bioscience Ltd., BioCity, Pennyfoot Street, NottinghamNG1 1GF, U. K.
  • Smith GCM; Artios Pharma Ltd., B940, Babraham Research Campus, CambridgeCB22 3FH, U. K.
  • Swarbrick ME; Cancer Research Horizons Therapeutic Innovation, Jonas Webb Building, Babraham Research Campus, CambridgeCB22 3AT, U. K.
  • Turnbull AP; Cancer Research Horizons Therapeutic Innovation, The Francis Crick Institute, 1 Midland Road, LondonNW1 1AT, U. K.
  • Willis S; Cancer Research Horizons Therapeutic Innovation, The Francis Crick Institute, 1 Midland Road, LondonNW1 1AT, U. K.
  • Heald RA; Artios Pharma Ltd., B940, Babraham Research Campus, CambridgeCB22 3FH, U. K.
J Med Chem ; 65(20): 13879-13891, 2022 10 27.
Article em En | MEDLINE | ID: mdl-36200480
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Reparo do DNA por Junção de Extremidades / Inibidores de Poli(ADP-Ribose) Polimerases Limite: Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Reparo do DNA por Junção de Extremidades / Inibidores de Poli(ADP-Ribose) Polimerases Limite: Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2022 Tipo de documento: Article