Elevated NRAS expression during DCIS is a potential driver for progression to basal-like properties and local invasiveness.

Zheng, Ze-Yi; Elsarraj, Hanan; Lei, Jonathan T; Hong, Yan; Anurag, Meenakshi; Feng, Long; Kennedy, Hilda; Shen, Yichao; Lo, Flora; Zhao, Zifan; Zhang, Bing; Zhang, Xiang H-F; Tawfik, Ossama W; Behbod, Fariba; Chang, Eric C

Zheng, Ze-Yi; Elsarraj, Hanan; Lei, Jonathan T; Hong, Yan; Anurag, Meenakshi; Feng, Long; Kennedy, Hilda; Shen, Yichao; Lo, Flora; Zhao, Zifan; Zhang, Bing; Zhang, Xiang H-F; Tawfik, Ossama W; Behbod, Fariba; Chang, Eric C.

Afiliação

Zheng ZY; Lester and Sue Smith Breast Center and Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, 77030, USA.
Elsarraj H; Department of Medicine, Baylor College of Medicine, Houston, TX, 77030, USA.
Lei JT; Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS, 66160, USA.
Hong Y; Lester and Sue Smith Breast Center and Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, 77030, USA.
Anurag M; Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS, 66160, USA.
Feng L; Lester and Sue Smith Breast Center and Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, 77030, USA.
Kennedy H; Lester and Sue Smith Breast Center and Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, 77030, USA.
Shen Y; Department of Pathogenic Organism Biology, Henan University of Chinese Medicine, Zhengzhou, People's Republic of China.
Lo F; Lester and Sue Smith Breast Center and Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, 77030, USA.
Zhao Z; Lester and Sue Smith Breast Center and Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, 77030, USA.
Zhang B; Lester and Sue Smith Breast Center and Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, 77030, USA.
Zhang XH; Lester and Sue Smith Breast Center and Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, 77030, USA.
Tawfik OW; Cancer Cell Biology Graduate Program, Baylor College of Medicine, Houston, TX, 77030, USA.
Behbod F; Lester and Sue Smith Breast Center and Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, 77030, USA.
Chang EC; Lester and Sue Smith Breast Center and Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, 77030, USA.

Breast Cancer Res ; 24(1): 68, 2022 10 18.

Article em En | MEDLINE | ID: mdl-36258226

Assuntos

Neoplasias da Mama; Carcinoma Ductal de Mama; Carcinoma Intraductal não Infiltrante; Humanos; Feminino; Carcinoma Intraductal não Infiltrante/genética; Carcinoma Intraductal não Infiltrante/patologia; Antígeno Ki-67/genética; Antígeno Ki-67/metabolismo; Carcinoma Ductal de Mama/patologia; Proteína Supressora de Tumor p53/genética; Neoplasias da Mama/patologia; Hibridização in Situ Fluorescente; Invasividade Neoplásica/genética; Invasividade Neoplásica/patologia; RNA Mensageiro; Progressão da Doença; Proteínas de Membrana/genética; Proteínas de Membrana/metabolismo; GTP Fosfo-Hidrolases/genética; GTP Fosfo-Hidrolases/metabolismo

Palavras-chave

Breast cancer; DCIS; Invasion; Premalignancy; Ras GTPase

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Carcinoma Ductal de Mama / Carcinoma Intraductal não Infiltrante Limite: Female / Humans Idioma: En Revista: Breast Cancer Res Assunto da revista: NEOPLASIAS Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

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