Introduction of a More Glutaredoxin-like Active Site to PDI Results in Competition between Protein Substrate and Glutathione Binding.

Saaranen, Mirva J; Alanen, Heli I; Salo, Kirsi E H; Nji, Emmanuel; Kärkkäinen, Pekka; Schmotz, Constanze; Ruddock, Lloyd W

Saaranen, Mirva J; Alanen, Heli I; Salo, Kirsi E H; Nji, Emmanuel; Kärkkäinen, Pekka; Schmotz, Constanze; Ruddock, Lloyd W.

Afiliação

Saaranen MJ; Protein and Structural Biology, Faculty of Biochemistry and Molecular Medicine, University of Oulu, 90220 Oulu, Finland.
Alanen HI; Protein and Structural Biology, Faculty of Biochemistry and Molecular Medicine, University of Oulu, 90220 Oulu, Finland.
Salo KEH; Research Unit of Biomedicine, Faculty of Medicine, University of Oulu, 90220 Oulu, Finland.
Nji E; Centre for Research in Therapeutic Sciences (CREATES), Strathmore University, Nairobi 59857-00200, Kenya.
Kärkkäinen P; BioStruct-Africa, Vårby, 14343 Stockholm, Sweden.
Schmotz C; Protein and Structural Biology, Faculty of Biochemistry and Molecular Medicine, University of Oulu, 90220 Oulu, Finland.
Ruddock LW; Research Program for Clinical and Molecular Metabolism, University of Helsinki, 00290 Helsinki, Finland.

Antioxidants (Basel) ; 11(10)2022 Sep 28.

Article em En | MEDLINE | ID: mdl-36290643

Palavras-chave

disulfide bond; glutaredoxin; glutathione; protein disulfide isomerase; redox; thioredoxin fold

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Antioxidants (Basel) Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Finlândia

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