Celastrol and Rhynchophylline in the mitigation of simulated muscle atrophy under <i>in vitro</i>.

Wastag, Maksymilian; Biezunska-Kusiak, Katarzyna; Szewczyk, Anna; Szlasa, Wojciech; Grimling, Bozena; Kulbacka, Julita

Celastrol and Rhynchophylline in the mitigation of simulated muscle atrophy under in vitro.

Wastag, Maksymilian; Biezunska-Kusiak, Katarzyna; Szewczyk, Anna; Szlasa, Wojciech; Grimling, Bozena; Kulbacka, Julita.

Afiliação

Wastag M; Faculty of Pharmacy, Wroclaw Medical University, Borowska 211A, 50-556, Wroclaw, Poland.
Biezunska-Kusiak K; Department of Molecular and Cellular Biology, Wroclaw Medical University, Borowska 211A 50-556, Wroclaw, Poland.
Szewczyk A; Department of Molecular and Cellular Biology, Wroclaw Medical University, Borowska 211A 50-556, Wroclaw, Poland.
Szlasa W; Department of Animal Developmental Biology, Institute of Experimental Biology, University of Wroclaw, Sienkiewicza 21, 50-335 Wroclaw, Poland.
Grimling B; Faculty of Medicine, Wroclaw Medical University, Pasteura 1, 50-367 Wroclaw, Poland.
Kulbacka J; Department of Drug Form Technology, Wroclaw Medical University, Borowska 211 A, 50-556 Wroclaw, Poland.

Saudi Pharm J ; 30(10): 1387-1395, 2022 Oct.

Article em En | MEDLINE | ID: mdl-36387339

Palavras-chave

Akt1, serine/threonine-protein kinase or AKT kinase 1; CLS, celastrol; Celastrol; DEX, dexamethasone; DOX, doxorubicin; ERK1/2, extracellular signal-regulated kinase 1/2; HSF1, Heat shock factor 1; HSP, heat shock protein; ICC, immunocytochemistry; MA, Muscular atrophy; MAFbx, Muscle Atrophy F-box gene; MMP, mitochondrial membrane potential; MTCO1, Mitochondrially Encoded Cytochrome C Oxidase I; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; MuRF1, Muscle RING Finger protein-1; Muscle atrophy; NLS, nuclear localization signals; RA, rheumatoid arthritis; Rhynchophylline; Ryn, Rhynchophylline; SMA, spinal muscular atrophy; Skeletal muscles; VDAC, voltage-dependent anion channel; mPTP, mitochondrial permeability transition pore

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Saudi Pharm J Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Polônia

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