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Elimusertib (BAY1895344), a novel ATR inhibitor, demonstrates in vivo activity in ATRX mutated models of uterine leiomyosarcoma.
Harold, Justin; Bellone, Stefania; Manavella, Diego D; Mutlu, Levent; McNamara, Blair; Hartwich, Tobias Max Philipp; Zipponi, Margherita; Yang-Hartwich, Yang; Demirkiran, Cem; Verzosa, Miguel Skyler; Choi, Jungmin; Dong, Weilai; Buza, Natalia; Hui, Pei; Altwerger, Gary; Huang, Gloria S; Andikyan, Vaagn; Clark, Mitchell; Ratner, Elena; Azodi, Masoud; Schwartz, Peter E; Santin, Alessandro D.
Afiliação
  • Harold J; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Bellone S; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Manavella DD; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Mutlu L; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • McNamara B; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Hartwich TMP; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Zipponi M; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Yang-Hartwich Y; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Demirkiran C; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Verzosa MS; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Choi J; Department of Biomedical Sciences, Korea University College of Medicine, 02841 Seoul, Republic of Korea.
  • Dong W; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA.
  • Buza N; Department of Pathology, Yale University School of Medicine, CT 06520, USA.
  • Hui P; Department of Pathology, Yale University School of Medicine, CT 06520, USA.
  • Altwerger G; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Huang GS; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Andikyan V; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Clark M; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Ratner E; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Azodi M; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Schwartz PE; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Santin AD; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA. Electronic address: alessandro.santin@yale.edu.
Gynecol Oncol ; 168: 157-165, 2023 01.
Article em En | MEDLINE | ID: mdl-36442427
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Uterinas / Leiomiossarcoma Limite: Animals / Female / Humans Idioma: En Revista: Gynecol Oncol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Uterinas / Leiomiossarcoma Limite: Animals / Female / Humans Idioma: En Revista: Gynecol Oncol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos