Repurposing BCL-2 and Jak 1/2 inhibitors: Cure and treatment of HIV-1 and other viral infections.

Reece, Monica D; Song, Colin; Hancock, Sarah C; Pereira Ribeiro, Susan; Kulpa, Deanna A; Gavegnano, Christina

Reece, Monica D; Song, Colin; Hancock, Sarah C; Pereira Ribeiro, Susan; Kulpa, Deanna A; Gavegnano, Christina.

Afiliação

Reece MD; Department of Pathology and Laboratory Medicine, School of Medicine, Emory University, Atlanta, GA, United States.
Song C; Department of Chemistry, College of Arts and Sciences, Emory University, Atlanta, GA, United States.
Hancock SC; Department of Biology, College of Arts and Sciences, Emory University, Atlanta, GA, United States.
Pereira Ribeiro S; Department of Pathology and Laboratory Medicine, School of Medicine, Emory University, Atlanta, GA, United States.
Kulpa DA; Department of Pathology and Laboratory Medicine, School of Medicine, Emory University, Atlanta, GA, United States.
Gavegnano C; Department of Pathology and Laboratory Medicine, School of Medicine, Emory University, Atlanta, GA, United States.

Front Immunol ; 13: 1033672, 2022.

Article em En | MEDLINE | ID: mdl-36569952

Assuntos

COVID-19; Infecções por HIV; HIV-1; Estados Unidos; Humanos; Latência Viral; Janus Quinases/metabolismo; Reposicionamento de Medicamentos; Transdução de Sinais; Fatores de Transcrição STAT/metabolismo; Proteínas Proto-Oncogênicas c-bcl-2/metabolismo

Palavras-chave

Bcl-2; HIV reservoir; HIV-1; Jak Stat; cancer; immunosenecence; inflammation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções por HIV / HIV-1 / COVID-19 Limite: Humans País/Região como assunto: America do norte Idioma: En Revista: Front Immunol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

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