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Alzheimer's disease-associated U1 snRNP splicing dysfunction causes neuronal hyperexcitability and cognitive impairment.
Chen, Ping-Chung; Han, Xian; Shaw, Timothy I; Fu, Yingxue; Sun, Huan; Niu, Mingming; Wang, Zhen; Jiao, Yun; Teubner, Brett J W; Eddins, Donnie; Beloate, Lauren N; Bai, Bing; Mertz, Joseph; Li, Yuxin; Cho, Ji-Hoon; Wang, Xusheng; Wu, Zhiping; Liu, Danting; Poudel, Suresh; Yuan, Zuo-Fei; Mancieri, Ariana; Low, Jonathan; Lee, Hyeong-Min; Patton, Mary H; Earls, Laurie R; Stewart, Elizabeth; Vogel, Peter; Hui, Yawei; Wan, Shibiao; Bennett, David A; Serrano, Geidy E; Beach, Thomas G; Dyer, Michael A; Smeyne, Richard J; Moldoveanu, Tudor; Chen, Taosheng; Wu, Gang; Zakharenko, Stanislav S; Yu, Gang; Peng, Junmin.
Afiliação
  • Chen PC; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Han X; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Shaw TI; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Fu Y; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Sun H; Integrated Biomedical Sciences Program, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
  • Niu M; Center for Proteomics and Metabolomics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Wang Z; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Jiao Y; Department of Biostatistics and Bioinformatics, Moffitt Cancer Center, Tampa, FL 33612, USA.
  • Teubner BJW; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Eddins D; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Beloate LN; Center for Proteomics and Metabolomics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Bai B; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Mertz J; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Li Y; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Cho JH; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Wang X; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Wu Z; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Liu D; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Poudel S; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Yuan ZF; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Mancieri A; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Low J; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Lee HM; Present address: Department of Biomedical Engineering and Electrical Engineering, Penn State University, State College, PA 16801, USA.
  • Patton MH; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Earls LR; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Stewart E; Present address: Department of Laboratory Medicine, Center for Precision Medicine, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, Jiangsu 210008, China.
  • Vogel P; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Hui Y; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Wan S; Present address: GlaxoSmithKline, Rockville, MD 20850, USA.
  • Bennett DA; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Serrano GE; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Beach TG; Center for Proteomics and Metabolomics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Dyer MA; Center for Proteomics and Metabolomics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Smeyne RJ; Integrated Biomedical Sciences Program, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
  • Moldoveanu T; Present address: Department of Biology, University of North Dakota, Grand Forks, ND 58202, USA.
  • Chen T; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Wu G; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Zakharenko SS; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Yu G; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Peng J; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Nat Aging ; 2(10): 923-940, 2022 10.
Article em En | MEDLINE | ID: mdl-36636325
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Alzheimer / Disfunção Cognitiva Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: Nat Aging Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Alzheimer / Disfunção Cognitiva Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: Nat Aging Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos