Synthesis, Antibacterial and Antiribosomal Activity of the 3<i>C</i>-Aminoalkyl Modification in the Ribofuranosyl Ring of Apralogs (5-<i>O</i>-Ribofuranosyl Apramycins).

Lubriks, Dmitrijs; Haldimann, Klara; Hobbie, Sven N; Vasella, Andrea; Suna, Edgars; Crich, David

Synthesis, Antibacterial and Antiribosomal Activity of the 3C-Aminoalkyl Modification in the Ribofuranosyl Ring of Apralogs (5-O-Ribofuranosyl Apramycins).

Lubriks, Dmitrijs; Haldimann, Klara; Hobbie, Sven N; Vasella, Andrea; Suna, Edgars; Crich, David.

Afiliação

Lubriks D; Latvian Institute of Organic Synthesis, Aizkraukles 21, LV-1006 Riga, Latvia.
Haldimann K; Institute of Medical Microbiology, University of Zurich, Gloriastrasse 30, 8006 Zürich, Switzerland.
Hobbie SN; Institute of Medical Microbiology, University of Zurich, Gloriastrasse 30, 8006 Zürich, Switzerland.
Vasella A; Organic Chemistry Laboratory, ETH Zürich, Vladimir-Prelog-Weg 1-5/10, 8093 Zürich, Switzerland.
Suna E; Latvian Institute of Organic Synthesis, Aizkraukles 21, LV-1006 Riga, Latvia.
Crich D; Department of Pharmaceutical and Biomedical Sciences, University of Georgia, 250 West Green Street, Athens, GA 30602, USA.

Antibiotics (Basel) ; 12(1)2022 Dec 24.

Article em En | MEDLINE | ID: mdl-36671225

Palavras-chave

aminoglycoside antibiotics; aminoglycoside modifying enzymes; antibacterials; antiribosomal activity; ribosomal methyltransferases

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Antibiotics (Basel) Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Letônia

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