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Determinants of exposure to polychlorinated biphenyls in the Italian population in the last decades.
Ingelido, Anna Maria; Abate, Vittorio; Abballe, Annalisa; De Filippis, Stefania Paola; Dellatte, Elena; De Luca, Silvia; Ferri, Fabiola; Fulgenzi, Anna Rita; Iacovella, Nicola; Iamiceli, Anna Laura; Marra, Valentina; Miniero, Roberto; Valentini, Silvia; De Felip, Elena.
Afiliação
  • Ingelido AM; Italian National Institute for Health, Viale Regina Elena 299, 00161, Rome, Italy. annamaria.ingelido@iss.it.
  • Abate V; Italian National Institute for Health, Viale Regina Elena 299, 00161, Rome, Italy.
  • Abballe A; Italian National Institute for Health, Viale Regina Elena 299, 00161, Rome, Italy.
  • De Filippis SP; Italian National Institute for Health, Viale Regina Elena 299, 00161, Rome, Italy.
  • Dellatte E; Italian National Institute for Health, Viale Regina Elena 299, 00161, Rome, Italy.
  • De Luca S; Italian National Institute for Health, Viale Regina Elena 299, 00161, Rome, Italy.
  • Ferri F; Italian National Institute for Health, Viale Regina Elena 299, 00161, Rome, Italy.
  • Fulgenzi AR; Italian National Institute for Health, Viale Regina Elena 299, 00161, Rome, Italy.
  • Iacovella N; Italian National Institute for Health, Viale Regina Elena 299, 00161, Rome, Italy.
  • Iamiceli AL; Italian National Institute for Health, Viale Regina Elena 299, 00161, Rome, Italy.
  • Marra V; Italian National Institute for Health, Viale Regina Elena 299, 00161, Rome, Italy.
  • Miniero R; Italian National Institute for Health, Viale Regina Elena 299, 00161, Rome, Italy.
  • Valentini S; Italian National Institute for Health, Viale Regina Elena 299, 00161, Rome, Italy.
  • De Felip E; Italian National Institute for Health, Viale Regina Elena 299, 00161, Rome, Italy.
Environ Sci Pollut Res Int ; 30(16): 47012-47024, 2023 Apr.
Article em En | MEDLINE | ID: mdl-36735124
ABSTRACT
Polychlorinated biphenyls (PCBs) are industrial products extensively used in the past. Because of their widespread presence and toxic effects, the international community adopted control measures to reduce their release into the environment. Currently, PCB concentrations are decreasing, but humans are still exposed. In this paper, we reported the results of a study concerning PCB concentrations in human serum samples collected in Italy over two decades. The aim of the study was to investigate the trend of major determinants of PCB human exposure, several decades after the end of their production. PCB concentrations ranged over three orders of magnitude (from 0.4 to 958 ng/g lipid), with a median value of 85 ng/g lipid. We identified age, sampling year, body mass index, sex, and living near hot spots or being occupationally exposed as relevant factors in determining body burden. Our results can give indications to refine regulatory policies on PCBs in Italy, with particular attention to the disposal of residue PCB-containing products. To improve control measures can further decrease the exposure of citizens to PCBs, limit health implications, and improve citizens' perception about chemical risk management.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bifenilos Policlorados Tipo de estudo: Prognostic_studies Limite: Humans País/Região como assunto: Europa Idioma: En Revista: Environ Sci Pollut Res Int Assunto da revista: SAUDE AMBIENTAL / TOXICOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Itália

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bifenilos Policlorados Tipo de estudo: Prognostic_studies Limite: Humans País/Região como assunto: Europa Idioma: En Revista: Environ Sci Pollut Res Int Assunto da revista: SAUDE AMBIENTAL / TOXICOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Itália