Versatile use of bat ACE2 for cellular entry by MERS-CoV-like viruses.

Baid, Kaushal; Banerjee, Arinjay

Baid, Kaushal; Banerjee, Arinjay.

Afiliação

Baid K; Vaccine and Infectious Disease Organization, University of Saskatchewan, Saskatoon, SK S7N 5E3, Canada.
Banerjee A; Vaccine and Infectious Disease Organization, University of Saskatchewan, Saskatoon, SK S7N 5E3, Canada; Department of Veterinary Microbiology, University of Saskatchewan, Saskatoon, SK S7N 5B4, Canada; Department of Biology, University of Waterloo, Waterloo, ON N2L 3G1, Canada; Department of Laboratory Medicine and Pathobiology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Bri

Cell Host Microbe ; 31(2): 161-163, 2023 02 08.

Article em En | MEDLINE | ID: mdl-36758513

ABSTRACT

ABSTRACT

Cellular entry receptors for bat MERS-CoV-like viruses NeoCoV and PDF-2180 were unknown, leaving their zoonotic potential ambiguous. A recent study by Xiong et al. published in Nature identified bat ACE2 as the cellular entry receptor for both viruses, highlighting the ability of coronaviruses to utilize a range of entry receptors.

Assuntos

Quirópteros; Infecções por Coronavirus; Coronavírus da Síndrome Respiratória do Oriente Médio; Animais; Humanos; Enzima de Conversão de Angiotensina 2; Linhagem Celular; Glicoproteína da Espícula de Coronavírus

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quirópteros / Infecções por Coronavirus / Coronavírus da Síndrome Respiratória do Oriente Médio Limite: Animals / Humans Idioma: En Revista: Cell Host Microbe Assunto da revista: MICROBIOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Canadá

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