Using multiple imputation of real-world data to estimate clinical remission in pediatric inflammatory bowel disease.

Zhang, Nanhua; Liu, Chunyan; Steiner, Steven J; Colletti, Richard B; Baldassano, Robert; Chen, Shiran; Cohen, Stanley; Kappelman, Michael D; Saeed, Shehzad; Conklin, Laurie S; Strauss, Richard; Volger, Sheri; King, Eileen; Lo, Kim Hung

Zhang, Nanhua; Liu, Chunyan; Steiner, Steven J; Colletti, Richard B; Baldassano, Robert; Chen, Shiran; Cohen, Stanley; Kappelman, Michael D; Saeed, Shehzad; Conklin, Laurie S; Strauss, Richard; Volger, Sheri; King, Eileen; Lo, Kim Hung.

Afiliação

Zhang N; Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Liu C; University of Cincinnati, Cincinnati, OH 45229, USA.
Steiner SJ; Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Colletti RB; Riley Hospital for Children/Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Baldassano R; University of Vermont College of Medicine, Department of Pediatrics, Burlington, VT 05405, USA.
Chen S; The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Cohen S; Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Kappelman MD; GI Care For Kids, Atlanta, GA 30342, USA.
Saeed S; Morehouse School of Medicine, Atlanta, GA 30310, USA.
Conklin LS; University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Strauss R; Dayton Children's Hospital/Wright State University, Dayton, OH 45404, USA.
Volger S; Janssen Research & Development, LLC, Spring House, PA 19477, USA.
King E; Janssen Research & Development, LLC, Spring House, PA 19477, USA.
Lo KH; Janssen Research & Development, LLC, Spring House, PA 19477, USA.

J Comp Eff Res ; 12(4): e220136, 2023 04.

Article em En | MEDLINE | ID: mdl-36799351

Assuntos

Doença de Crohn; Doenças Inflamatórias Intestinais; Humanos; Criança; Doença de Crohn/tratamento farmacológico; Reprodutibilidade dos Testes; Resultado do Tratamento; Indução de Remissão

Palavras-chave

ImproveCareNow registry; Short Pediatric Crohn's Disease Activity Index (sPCDAI); clinical remission status; disease-specific patient registries; drug repurposing and relabeling; inflammatory bowel disease; missing data; multiple imputation method; pediatric Crohn's disease; real-world evidence

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Inflamatórias Intestinais / Doença de Crohn Limite: Child / Humans Idioma: En Revista: J Comp Eff Res Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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