Modern treatment of sinonasal undifferentiated carcinoma.
Curr Opin Otolaryngol Head Neck Surg
; 31(2): 89-93, 2023 Apr 01.
Article
em En
| MEDLINE
| ID: mdl-36912221
ABSTRACT
PURPOSE OF REVIEW Sinonasal undifferentiated carcinomas are rare aggressive tumours with traditionally poor outcomes. Although multimodality treatment has been recommended by most centres, the ideal treatment sequence or regimen has not been established. RECENT FINDINGS:
Recent evidence suggests that induction chemotherapy may be used for chemoselection and cytoreduction prior to definitive chemoradiotherapy. Where there is a favourable response, concurrent chemoradiotherapy is favoured, with an improved overall survival and improved rates of organ preservation.SUMMARY:
Induction chemotherapy may be a useful guide for selection of patients for chemoradiotherapy or surgery and has shown encouraging results. Further research is required to establish the ideal induction chemotherapy regimen for this rare group of tumours.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias do Seio Maxilar
/
Carcinoma
Limite:
Humans
Idioma:
En
Revista:
Curr Opin Otolaryngol Head Neck Surg
Assunto da revista:
OTORRINOLARINGOLOGIA
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
Singapura