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High-throughput Sequencing to Identify Bacteremia in Children with Cancer.
McLaren, Son H; Mishra, Nischay; Hijiya, Nobuko; Ng, James; Guo, Cheng; Whittier, Susan; Mariani, Erica; Glaser, Laura; Frantzis, Irene; Vindas, Marc T; Leu, Cheng-Shiun; Dayan, Peter S.
Afiliação
  • McLaren SH; From the Division of Pediatric Emergency Medicine, Department of Emergency Medicine, Columbia University Vagelos College of Physicians and Surgeons, New York, NY.
  • Mishra N; Department of Epidemiology, Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY.
  • Hijiya N; Division of Pediatric Hematology Oncology and Stem Cell Transplant, Department of Pediatrics, Columbia University Vagelos College of Physicians and Surgeons, New York, NY.
  • Ng J; Department of Epidemiology, Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY.
  • Guo C; Department of Epidemiology, Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY.
  • Whittier S; Department of Pathology and Cell Biology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY.
  • Mariani E; Department of Pediatrics, New York University Langone Medical Center/Bellevue Hospital Center, New York, NY.
  • Glaser L; Department of Pediatrics, Pediatric Hematology Oncology and Stem Cell Transplant Clinic, New York-Presbyterian Morgan Stanley Children's Hospital, New York, NY.
  • Frantzis I; Department of Pediatrics, Columbia University Vagelos College of Physicians and Surgeons, New York, NY.
  • Vindas MT; The Cancer Center at Cooperman Barnabas Medical Center, Rutgers Cancer Institute of New Jersey, Livingston, NJ.
  • Leu CS; Department of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY.
  • Dayan PS; From the Division of Pediatric Emergency Medicine, Department of Emergency Medicine, Columbia University Vagelos College of Physicians and Surgeons, New York, NY.
Pediatr Infect Dis J ; 42(8): 695-697, 2023 08 01.
Article em En | MEDLINE | ID: mdl-37171915
Current methods to diagnose bacteremia are limited. In this pilot study of children with cancer presenting with fever, we determined the concordance between a novel high-throughput sequencing platform called BacCapSeq and blood culture. High-throughput sequencing had modest concordance with blood culture. Discordant organisms included those with both unlikely or potential clinical relevance.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bacteriemia / Neoplasias Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Child / Humans / Infant Idioma: En Revista: Pediatr Infect Dis J Assunto da revista: DOENCAS TRANSMISSIVEIS / PEDIATRIA Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bacteriemia / Neoplasias Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Child / Humans / Infant Idioma: En Revista: Pediatr Infect Dis J Assunto da revista: DOENCAS TRANSMISSIVEIS / PEDIATRIA Ano de publicação: 2023 Tipo de documento: Article