Coronary Artery Disease Risk Prediction in Young Adults: How Can We Overcome the Dominant Effect of Age?
Curr Atheroscler Rep
; 25(6): 257-265, 2023 06.
Article
em En
| MEDLINE
| ID: mdl-37195598
ABSTRACT
PURPOSE OF REVIEW We review the limitations of current approaches for predicting Coronary Artery Disease (CAD) in young adults and explore the alternative approaches identify high-risk individuals in this population. RECENT FINDINGS:
Atherosclerosis begins in childhood, and young individuals with genetic predisposition and individuals with early exposure to traditional and non-traditional risk factors have an increased lifetime risk of CAD. However, most risk prediction models have been developed and validated in middle and older age groups and focus on short-term risk. Therefore, alternative approaches are needed in younger individuals. Genetic scores, biomarkers, imaging studies, and multi-omics data all have the potential to be used and help identify high-risk individuals.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doença da Artéria Coronariana
/
Aterosclerose
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Humans
Idioma:
En
Revista:
Curr Atheroscler Rep
Assunto da revista:
ANGIOLOGIA
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
Estados Unidos